卵巢癌的蛋白质谱及超声造影诊断研究  

Research on protein profiling and contrast-enhanced ultrasound in diagnosis of ovarian cancer

作　　者：张月梅[1] 莫捷[1] 

机构地区：[1]深圳市宝安区妇幼保健院,广东深圳518110

出　　处：《中国妇幼健康研究》2011年第4期529-530,共2页Chinese Journal of Woman and Child Health Research

摘　　要：目的探讨蛋白质谱与超声造影对于卵巢癌临床诊断的准确性。方法对宝安区妇幼保健院103例被怀疑为卵巢癌的患者进行蛋白质谱与超声造影检测，分别做出诊断结果，与最终病理、术后或化疗确诊结果进行对比分析。结果蛋白质谱对恶性肿瘤的诊断准确率为87．88％，超声造影对恶性肿瘤的诊断准确率为93．94％；蛋白质谱与确诊结果间呈正相关性（r=0．9936，P〈0．01）；超声造影与确诊结果间呈正相关性（r=0．9981，P〈0．01），差异具有统计学意义。结论蛋白质谱及超声造影可有效提高卵巢癌的临名床诊断准确率，对于卵巢癌的早期诊断具有十分重要的参考价值。．Objective To explore the diagnostic accuracy of protein profiling and contrast-enhanced ultrasound in diagnosis of ovarian cancer. Metlaotb Protein profiling and contrast-enhanced ultrasonography were performed on 103 cases suspected of suffering from ovarian cancer in our hespital, and the diagnosis results were analyzed and compared with the final diagnosis results of pathology, operation and chemotherapy. Results The diagnostic accuracy rate of protein profiling and contrast-enhanced ultrasound on malignant tumor was 87.88% and 93.94%, respectively. The diagnostic results of protein profiling and contrast-enhanced ultrasound were positively related with the final diagnosis （0 〈 r 〈 1 ）. Conclusion Protein profiling and contrast-enhanced ultrasonic imaging can increase the accuracy of clinical t＇lln^nnala nf nv^n aAnt^ar whlah hng vgrv imnnrtAnt rgfgrgnop ,trA｜nS in gnrlv rtiAtrnnala nf nvnHnn t, nnot^r

关 键 词：卵巢癌 蛋白质谱 超声造影 诊断研究 

分 类 号：R446.1[医药卫生—诊断学] R445.1[医药卫生—临床医学]