肿瘤患者感染铜绿假单胞菌的现状与对策  

Current status of Pseudomonas aeruginosa infections in tumour patients and countermeasures

作　　者：陈燕[1] 陈丽妹[1] 辛娜[1] 刘燕玉[1] 

机构地区：[1]福建省肿瘤医院检验科,福建福州350014

出　　处：《中华医院感染学杂志》2011年第15期3164-3165,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解肿瘤患者感染铜绿假单胞菌的现状,并制定对策。方法分析2007-2009年检出的440株铜绿假单胞菌的分离率及耐药性,采用K-B纸片扩散法结合VITEK-2 MIC法进行药敏试验,按美国临床实验室标准化研究所(CLSI)标准判断结果。结果近3年分离出铜绿假单胞菌不断上升,2007-2009年分离率分别为7.94%、11.15%、15.91%;细菌分离以痰标本分离率最高,占65.68%,其次是分泌物,占12.50%,引流液占7.50%;铜绿假单胞菌耐药率呈上升趋势。结论铜绿假单胞菌是引起医院感染的重要病原菌之一,应合理使用抗菌药物,加强医院感染管理,避免交叉感染。OBJECTIVE To investigate the infection among tumoral inpatients in hospital and find out the quick path of preventing hospital infection.METHODS The drug-resistance of 440 Pseudomonas aeruginosa isolates to 12 kinds of common antibiotics was performed by K-B method and by MIC through the VITEKⅡ.The drug sensitivity test was performed based on the standard of the CLSI of the USA during 2007-2009.RESULTS The isolation rate of Pseudomonas aeruginosa was increased during the last 3 years,the strains were mainly isolated from esophageal neoplasms,the isolation rates from 2007-2009 were 7.94%,11.15% and 15.91%,respectively.The bacteria were mainly isolated from lower sputum,secretion and drainage of fluid,accounting for 65.68%,12.50% and 7.50%,respectively.The resistant rate was increased.CONCLUSION P.aeruginosa is the important pathogen causing hospital infection,rational use of antibiotics is very important,we should strengthen the administration and controlling of nosocomial infections.

关 键 词：铜绿假单胞菌 肿瘤患者 感染 对策 

分 类 号：R378.991[医药卫生—病原生物学]