医务人员混合感染甲型H1N1及B型流感病毒的调查  

Investigation of mixed infection with influenza A(H1N1) and seasonal B viruses in medical staff

作　　者：刘建明[1] 刘大钺[1] 杨永洁[1] 黄美清[1] 林澜溪[1] 谢灿茂[2] 

机构地区：[1]中山大学附属第一医院医院感染管理科,广东广州510080 [2]中山大学附属第一医院医院呼吸内科,广东广州510080

出　　处：《中华医院感染学杂志》2011年第15期3198-3200,共3页Chinese Journal of Nosocomiology

基　　金：广东省科技计划项目(2008A030201029)

摘　　要：目的及时总结经验,为医院预防控制甲型H1N1流感提供参考。方法采用现场流行病学调查方法,对发生在某医院骨肿瘤病区的一起流感疫情进行调查分析,开展监测以评价疫情控制效果。结果共发现12例感染病例,罹患率10.81%,首发病例为1名医师;共采集8份咽拭子标本,7份标本甲型H1N1流感病毒核酸阳性,1份标本同时检测到甲型H1N1流感及B型流感病毒;感染对象均为医务人员,护士9名,医师3名,护士罹患率为45.0%,医师罹患率为12.0%,差异有统计学意义(χ2=6.188,P<0.05);监测未发现住院患者出现发热及流感样症状,未发现疫情扩散至其他病区,该次疫情在4 d内得到有效控制。结论该事件为一起以医务人员感染甲型H1N1流感病毒为主的疫情;应加强医务人员健康监测及个人防护教育;早发现、早报告并及时采取综合的医院感染预防控制措施是有效控制医院感染暴发的关键。OBJECTIVE To summarize the experience and to provide reference for prevention and control influenza in hospital.METHODS The outbreak of influenza happened in bone tumour ward of a hospital was investigated by using field epidemiology survey,and the effectiveness of control strategy was evaluated through surveillance.RESULTS A total of 12 cases were infected with influenza in the outbreak with attack rate 10.81%.The first case was confirmed with a doctor.Of 8 throat swabs samples collected and detected by RT-Realtime for both pandemic H1N1,season A and season B viruses,7 of 8 were positive result for pandemic H1N1,and 1 was positive result both for pandemic H1N1 and seasonal B viruse.All the patients were medical staff,consisting of 9 nurses and 3 surgeon in bone tumour ward in a hospital.There were significant statistical difference（χ2=6.188,P0.05）in incidences of nurses（12.0%） and doctors（45.0%） group.Surveillance showed that no inpatient had fever or influenza-like illness symptoms,and no epidemic situation diffused to the other departments in the hospital.The outbreak was terminated within 4 days.CONCLUSION This event is a medical staff co-infected with pandemic H1N1 and seasonal B viruses outbreak happened in a hospital.Health monitoring and education about self-protection of medical staff should be enhanced in hospital.Timely detecting,reporting and multiple hospital infection control measures are the keys to control the outbreak of nosocomial infection.

关 键 词：甲型H1N1流感 混合感染 医务人员 医院感染 

分 类 号：R181.32[医药卫生—流行病学]