儿科住院患者呼吸道感染病原菌分布及耐药性分析  

Distribution and drug resistance of pathogenic bacteria causing respiratory tract infection in pediatric inpatients

作　　者：张传飞[1] 李爱娟[1] 庞佩芬 

机构地区：[1]浙江省天台县人民医院检验科,浙江天台县317200

出　　处：《中华医院感染学杂志》2011年第15期3283-3285,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解和探讨儿科住院患者呼吸道感染的主要病原菌及耐药性,为临床诊断与治疗提供实验室依据。方法对2005年1月-2007年12月儿科送检痰标本中检出的病原菌,采用全自动细菌鉴定仪VITEK-32进行细菌鉴定和药敏试验,结合K-B药敏试验方法。结果共分离出病原菌203株,以革兰阴性杆菌为主,占52.2%,革兰阳性球菌占11.3%,真菌占36.5%,按分离率高低,排在前3位病原菌依次为肺炎克雷伯菌、大肠埃希菌、金黄色葡萄球菌分别占20.9%、19.4%、17.8%。结论临床在抗菌药物使用中应加强病原菌检测,根据药敏结果科学选药,提高治疗效果,延缓细菌对抗菌药物耐药性的产生。OBJECTIVE To understand and discuss the main pathogens causing respiratory tract infections and drug resistance,to provide laboratory reference for clinical diagnosis and treatment.METHODS From Jul 2005 to Jun 2008,the strains from phlegm specimen of the department of pediatrics were identified out by using the completely automatic identification of bacteria meter called VITEK-32 to carry on the identification of bacteria and medicine sensitive experiment,unifies the K-B medicine sensitive testing method.RESULTS The pathogens were altogether separated out 203 and were primarily for Gram-negative bacillus,accounting for 52.2%,Gram-positive cocci accounted for 11.3%,the fungi accounted for 36.5%.The top 3 three pathogens with the highest detection rates were K.pnenmomiae,Escherichia coli and S.aureus,accounting for 20.9%,19.4% and 17.8%,respectively.CONCLUSION The clinic should strengthen the pathogens inspection for reasonable use of antibiotics,the antibiotics should be scientifically selected based on the drug susceptibility test,in order to improve curative efficacy and delay the occurrence of bacterial resistance.

关 键 词：病原菌 呼吸道感染 耐药性 

分 类 号：R378[医药卫生—病原生物学]