148例肺结核合并真菌感染或定植的临床特点及耐药分析  

Clinical distribution and drug resistance of 148 cases of tuberculosis combined with fungal infection or colonization

作　　者：杨丽梅[1] 蔡红[1] 班武娟[1] 宋长兴[1] 

机构地区：[1]北京胸科医院检验科,北京101149

出　　处：《中华医院感染学杂志》2011年第15期3301-3303,共3页Chinese Journal of Nosocomiology

摘　　要：目的探讨肺结核合并真菌感染或定植的临床特点。方法回顾2009年1月-2010年7月医院住院的肺结核合并肺部真菌感染或定植患者的资料并进行分析。结果肺结核合并真菌感染或定植主要以老年、低蛋白血症、糖尿病、合并肺部细菌感染患者为主,其分别占33.11%、33.11%、21.62%、40.54%;检出的病原菌以白色假丝酵母菌为主,占75.68%;148例感染患者死亡8例,死亡率为5.41%。结论肺结核合并肺部真菌感染或定植的患者有增多趋势,应重视真菌的变迁及耐药菌株的发生。OBJECTIVE To investigate the clinical features of pulmonary tuberculosis combined with fungal infection or colonization.METHODS Review and analysis were made on the records of pulmonary tuberculosis companied by fungal infection or colonization of patients who were admitted to our hospital for the past one and a half years.RESULTS Pulmonary tuberculosis combined with fungal infection or colonization mainly occurs in elder patients（33.11%）,patients with hypoproteinemia（75.68%）,patients afflicted with diabetes（21.62%）,those patients coupled with pulmonary bacterial infection（40.54%）.Pathogenic bacteria were mainly made of Candida albicans,8 cases were dead with the mortality of 5.41%.CONCLUSION There′s a growing trend in pulmonary fungal infection or colonization in TB patients,thus attention should be paid to variation of fungi and the occurrence of drug resistant strains.

关 键 词：肺结核 真菌感染 耐药 

分 类 号：R379[医药卫生—病原生物学]