针吸细胞学检查及药物局部注射在女性前列腺炎诊治中的应用研究  

Study of needle aspination cytology and local drug injection in the treatment of female prostatitis

作　　者：丁新民[1] 蒋国华[1] 温洪波[1] 何锦园[1] 王炜[1] 

机构地区：[1]广东省东莞市虎门医院,523902

出　　处：《中国医学创新》2011年第23期12-14,共3页Medical Innovation of China

基　　金：广东省东莞市科研基金项目(项目编号:2009105150113)

摘　　要：目的研究应用针吸细胞学检查帮助诊断女性前列腺炎及在"女性前列腺"局部注射抗生素用于治疗女性尿道综合征的可行性,为其探索一种有效的诊治方法。方法选择2009年7月～2010年12月在本院门诊就诊的患者163例。随机分为A、B、C三组,A组58冽为实验组,B组55例、C组50例为对照组。A、B、C三组均进行同样的常规治疗,除此之外A、B组同时采取局部注射治疗,注射前先行穿刺细胞学检查,A组注射庆大霉素8万U(2 ml)+2%利多卡因2 ml的混合药液,B组注射生理盐水2 ml+2%利多卡因2 ml的混合药液。注射方法两组完全一致。浸润性注射在尿道后壁尿道旁腺及其周围,每周治疗2次,6次为1疗程。根据患者自主症状评分的改变评定疗效。疗程前及疗程结束后第2周、4周重复症状评分。结果 113例行针吸细胞学检查的患者中尿道旁腺周围提示急慢性炎症的71例(62.8%),对照部位穿刺阳性者53例(46.9%%),差异有统计学意义(P=0.02)。疗程结束后第2周症状评分,A组疗效(有效率为77.5%%、)明显高于B组(有效率为67.3%)和C组(有效率为68.0%),差异有统计学意义(P<0.05),而B、C组间差异无统计学意义(P>0.05)。疗程结束后第4周复查,A组有效率略有下降,仍然高于B组和C组,差异有统计学意义(P<0.05)。结论 "女性前列腺"局部穿刺细胞学检查可以帮助诊断女性前列腺炎,注射抗生素为女性尿道综合征的治疗提供了一个安全、简单、有效的方法 。Objective To investigate the feasibility of needle aspination cytology and local drug injection in the fe- male prostate in the treatment of female prostatitis. And then to explore an effective treatment to the female urethral syndrome. Methods in our out - patient department 163 patients suffered from female urethral syndrome were selected prospectively from July 2009 to December 2010. According to visiting orders, the 163 cases were randomly assigned to three groups named group A/B/C prospectively. The group A composed of 58 patients were experiment group, while group B composed of 55 ca- ses and group C composed of 50 ones were control groups. The patients of group A and B were performed by needle aspination cytology into and around the female prostate just before local drug injection. All the patients in the three groups were treated with routine measures. In addition, eighty thousand units of gentamycin and 2ml of lidocaine with one percent concentration were injected together to the distal segn^ent of urethral back wall where the female prostate was located 2 times a week,6 times in one course treatment. In group B, the same method were used but physiological saline substituted for gentamycin. The cura- tive effect was evaluated by using the changes of independent symptom scores evaluated by patients themselves. Symptom scores were evaluated repeatedly in the second and fourth week after one course treatment. If the symptom disappeared the effect was cure, if the score reduced 〉 1/2 was evident effect, 1/2 〉 1/4 was helpful effect, 〈 1/4 or increased was no effect. Results There were no differences on their ages, body weights, courses of disease and symptom scores evaluated be- fore the treatment, between the three groups（ P 〉0. 05 ）. 71 cases performed by needle aspination cytology were found acute and chronic inflammation. In the second week after one course treatment by total curative effect group A （ effective rate 77.5 % ）was better than group B （67.3 % ）and C （68.0%）, the diffe

关 键 词：女性尿道综合征 女性前列腺炎 药物局部注射治疗 针吸细胞学 

分 类 号：R697.33[医药卫生—泌尿科学]