耐甲氧西林金黄色葡萄球菌感染的流行病学及耐药性研究  

Epidemiology and resistance to antibiotics of methicillin-resistant Staphylococcus aureus

作　　者：药小萍[1,2] 吴学勇[1,2] 翁丽贞[1,2] 袁剑庆[1,2] 

机构地区：[1]上海市静安区中心医院 [2]华山医院静安分院感染管理科,上海200040

出　　处：《中华医院感染学杂志》2011年第16期3483-3485,共3页Chinese Journal of Nosocomiology

摘　　要：目的探讨城市中心城区耐甲氧西林金黄色葡萄球菌(MRSA)感染的流行病学及耐药性。方法采用回顾性调查方法,对医院2009年住院患者进行MRSA感染的统计分析。结果在2009年40 846份标本中,检出265株金黄色葡萄球菌,检出率为0.65%;265株金黄色葡萄球菌检出MRSA 229株,检出率为86.42%;MRSA229株中9株是院内MRSA感染,占3.93%;220株为社区MRSA感染,占96.07%;该菌株对临床常用10种抗菌药物的耐药率>60.00%,但对万古霉素的敏感率为100.00%。结论城市中心城区社区MRSA感染现状已相当严重,应当和地段医院或社区医院一起加强MRSA的预防及治疗工作。OBJECTIVE To investigate the epidemiology and resistance to antibiotics of methicillin-resistant Staphylococcus aureus in city center district hospital.METHODS Retrospective review was adopted to analyze MRSA infection from hospital inpatients in 2009.RESULTS Totally 265 strains S.aureus were isolated in 40 846 submitted samples in 2009,the detection rate was 0.65%.229 strains were MRSA,the detection rate accounted for 86.42%,9 strains of 229 strains MRSA were hospital-acquired MRSA infection,accounting for 3.93%;220 strains MRSA are community-acquired MRSA infections,accounting for 96.07%.Resistant rate of MRSA to 10 clinical common used antibiotics was higher than 60%,but sensitive rate of MRSA to vancomycin was 100.00%.CONCLUSION Due to the CA-MRSA infection is so serious in city center district hospital,we should fully strengthen the prevention and treatment function of MRSA with lot hospitals or community hospitals.

关 键 词：耐甲氧西林金黄色葡萄球菌 医院感染 社区感染 

分 类 号：R378[医药卫生—病原生物学]