甲状腺激素系列测定在临床中的初步评估  

Preiliminary evalution of clinical of thyroxine series determination

作　　者：贾建成[1] 李江疆[1] 何丹[1] 

机构地区：[1]宁夏自治区人民医院,宁夏银川750021

出　　处：《宁夏医学杂志》1999年第12期719-720,共2页Ningxia Medical Journal

摘　　要：目的　对甲状腺疾病患者进行甲状腺激素的系列测定（Ｔ３ 、Ｔ４ 、ｒＴ３ ，ＴＳＨ），探讨其临床应用价值。方法　采用ＲＩＡ 法检测对照组１０５ 例与病例组１５３ 例，其中甲亢组９５ 例，甲减组２３ 例，单纯性甲状腺肿组１６ 例， 非甲状腺病组１９ 例的血清甲状腺激素的系列测定作比较分析。结果　各项数据表明甲亢组、甲减组与对照组比较差异非常显著（ Ｐ＜ ０．０１） ，单纯性甲状腺肿与对照组比较差异不显著（ Ｐ＞０ ．０５） ，但与甲亢组、甲减组比较差异非常显著（ Ｐ＜０ ．０１），非甲状腺疾病组与对照组比较差异非常显著（ Ｐ＜ ０．０１）。结论　甲状腺激素的系列测定不仅对甲状腺疾病的鉴别诊断、观察疗效、判断预后着重要的作用，而且对宁夏地区甲状腺肿地方病的调查研究提供客观的依据。Objectives To test the serum thyroxine(T 3、T 4、rT 3、TSH) of the patients with Thyroid diseases and research its value in clinical practicace.Methods The RIA method was used to detemine the serum throxine levei in 105 cases as control group.153 cases of patients group.The 153cases in cluded 95 hyperthyroidism 23 hypothyroidism 16 simple goiter 19 without thyroid diseases to determine the serum thyroxine level and the results were compared and analysed.Results The date showed that there were significant difference between hyperthyroidism.Hypothyroidism and control groups(P<0.01).No significant difference seenbetween simple goiter and control group(P>0.05) but significant difference seen in hypertheroidism and hypothyroidism groups(P<0.01) and very significant difference was seen between non-thyroid diseases and control groups(P<0.01).Conclusions Thy roxine series determination can not only be used in differentiation diagnosis of thyroid abnormality and observation of therapeutic effect but offer objective evidences for research of goiter in Ningxia also.

关 键 词：甲状腺激素 甲状腺疾病 诊断 

分 类 号：R581.04[医药卫生—内分泌]