慢性鼻-鼻窦炎患者窦腔的细菌分布及药敏观察  

Microbial profile and antibiotic susceptibility of chronic rhinosinusitis

作　　者：肖立智[1] 郑静[1] 杨蕾[1] 陈劲海[1] 卢颖深[1] 卢珊[1] 张孝文[1] 

机构地区：[1]广州医学院第一附属医院耳鼻咽喉头颈外科,广州510120

出　　处：《临床耳鼻咽喉头颈外科杂志》2011年第15期692-694,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:了解慢性鼻-鼻窦炎(CRS)患者窦腔的细菌分布及药敏情况。方法:收集51例CRS手术患者窦腔脓液和病变黏膜行细菌培养和药敏试验,分析监测结果。结果:51例送检标本,阳性41例,阳性率为80.39%,其中表皮葡萄球菌17株,克氏库克菌3株,烟曲菌、铜绿假单胞菌、产气肠杆菌、粪肠球菌各2株,金黄色葡萄球菌等18个菌种各1株。分离菌株对常用抗生素敏感度:万古霉素100%,莫西沙星100%,左旋氧氟沙星92.31%,利福平90.91%,环丙沙星81.58%,复方新诺明67.65%,阿奇霉素47.62%,克拉霉素45.00%,氨苄西林/舒巴坦35.90%,头孢曲松钠39.39%,头孢呋辛钠30.43%,青霉素8.33%。结论:CRS多伴有细菌感染,喹诺酮类可作为内镜鼻窦手术后的首选抗生素。Objective：To investigate distribution and drug-susceptibility of bacteria in patients with chronic rhinosinusitis.Method：The purulent discharges or mucous membrane lesions were collected from the sinus of 51 patients with chronic rhinosinusitis receiving sinus surgery.The clinical specimens were incubated and the drug susceptibility was analyzed.Result：Of 51 specimens,41（80.39%） showed positive results in bacteria culture.The antibiotic susceptibility was as follows： vancomycin-100%,moxifloxacin-100%,levofloxacin-92.31%,rifampin-90.91%,ciprofloxacin-81.58%,SMZ-TMP-67.65%,azithromycin-47.62%,larithromycin-45.00%,ampicillin sodium and sulbactam sodium-35.90%,cefatriaxone-39.39%,cefuroxime sodium-30.43%,penicillin-8.33%.Conclusion：There are bacteria infections in most of chronic rhinosinusitis.The fluroquinolones should be preferred in sinus surgery.

关 键 词：慢性鼻-鼻窦炎 细菌培养 药敏试验 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]