pH滴定法测定羟乙膦酸钠的含量  

Determination of etidronate disodium by pH titralion method

作　　者：吴宏斌[1] 魏宇宁[2] 陈丽艳 

机构地区：[1]佳木斯大学药学院 [2]北京市301陆军总院药材处 [3]黑龙江省医药销售总公司格拉雷制药厂

出　　处：《黑龙江医药科学》1999年第6期22-22,共1页Heilongjiang Medicine and Pharmacy

摘　　要：本文采用pH滴定法，以pH5.0为起始pH，pH8．2为终点指示pH，用NaOH直接滴定，测定了羟乙膦酸钠的含量。该方法简便、准确快速，平均回收率为100．72％，RSD为0．23％（n＝6）．Etidronate disodium was determined quantitatively by pH titraion method. The initial pH was pH 5.0 and the terminal pH was pH 8.2, with 0. 1mol/L of NaOH as the titration sotution. This method was simple, accurae and quick. The average recovery and the retative standard diviation were 100.72% and 0.23%（n=6）

关 键 词：羟乙膦酸钠 PH滴定法 测定 

分 类 号：R971.8[医药卫生—药品]