黄芪注射液致过敏性休克21例文献分析  被引量:4

Literature Analysis of 21 Cases of Anaphylactic Shock Induced by Astragalus membranaceus Injection

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作  者:许静[1] 罗琳[1] 王珊珊[1] 徐康康[1] 

机构地区:[1]南京医科大学附属南京儿童医院,南京市210008

出  处:《中国药房》2011年第32期3029-3031,共3页China Pharmacy

摘  要:目的:探讨黄芪注射液致过敏性休克的特点及相关因素,促进临床合理用药。方法:检索中国学术文献网络出版总库、中国医院数字图书馆、万方数据资源系统及维普资讯网,筛选1995-2010年收载的中文医药卫生期刊中黄芪注射液致过敏性休克的报道21例,建立相关数据库以统计、分析。结果:21例过敏性休克中,有16例年龄在40岁以上,占调查病例的76.19%;男性11例(52.38%),女性10例(47.62%),均为静脉滴注给药;首次用药即出现过敏性休克症状的有14例(66.67%);过敏性休克发生的时间多在用药5min内,共8例(38.10%)。结论:临床应高度重视黄芪注射液引起的过敏性休克不良反应,以确保用药安全。OBJECTIVE:To discuss the characteristics and related factors of anaphylactic shock induced by Astragalus membranaceus injection, and to provide references for clinical drug use . METHODS: Retrieved from CNKI, CHKD, Wanfang database and VIP, 21 cases of A. membranaceus injection-induced anaphylactic shock reported in Chinese medical science journals during the period of 1995-2010 were collected. A related database was established for statistical analysis. RESULTS: Of 21 cases, 16 cases occurred in patients aged over 40 years, accounting for 76.19%; 11 were male (52.38%), 10 were female (47.62%); all were intravenous infusion. 14 patients suffered from anaphylactic shock after the initial administration (66.67%). Anaphylactic shock mostly occurred within 5 min after administration, and there were 8 cases (38.10%). CONCLUSION: Careful attention should be paid to the adverse drug reaction of anaphylactic shock induced by A. membranaceus injection in clinical practice to ensure safe drug use.

关 键 词:黄芪注射液 过敏性休克 文献分析 

分 类 号:R969.3[医药卫生—药理学]

 

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