颈动脉粥样硬化与不同类型冠心病的相关性分析  

The Relativity Analysis of Carotid Atherosclerosis and Various Coronary Heart Disease

作　　者：吴明祥[1] 陈运枝[1] 方丽娅[1] 杨遇春[1] 

机构地区：[1]武汉亚洲心脏病医院心内科,湖北省武汉市430000

出　　处：《中国动脉硬化杂志》2011年第9期773-776,共4页Chinese Journal of Arteriosclerosis

摘　　要：目的了解冠心病患者颈动脉粥样硬化的发病率;分析冠心病患者颈动脉粥样硬化的相关危险因素;探讨冠心病患者颈动脉粥样硬化程度与冠状动脉粥样硬化程度的关系;总结不同类型冠心病患者颈动脉粥样硬化病理特点。方法回顾性分析了228例经冠状动脉造影确诊为冠心病的病例冠状动脉造影结果、颈动脉超声检测结果及相关危险因素;根据颈动脉是否有粥样硬化分为粥样硬化组及非粥样硬化组;根据国际卫生组织诊断标准将病例分为稳定型心绞痛组、不稳定型心绞痛组及心肌梗死组;根据冠状动脉造影结果将病例分为单支病变组、双支病变组、三支病变组及左主干组;对颈动脉粥样硬化程度进行积分处理。结果发现228例冠心病患者中198例均有不同程度颈动脉粥样硬化,发病率86.8%;颈动脉粥样硬化与高血压显著相关,与年龄、性别、体质指数、吸烟、嗜酒、高脂血症、高尿酸血症及糖尿病无明显相关;颈动脉粥样硬化程度随冠状动脉粥样硬化的程度加重而加重,但仅仅单支病变组总斑块数显著低于左主干组(P<0.05);稳定型心绞痛组的颈动脉等级积分、Crouse积分均低于不稳定型心绞痛组;稳定型心绞痛组颈动脉等级积分较急性心肌梗死组低,而Crouse积分高于急性心肌梗死组;稳定型心绞痛组的总斑块数、扁平斑数及软斑数均低于不稳定型心绞痛组及急性心肌梗死组,3组的硬斑数无明显差别。3组均未发现溃疡斑。结论颈动脉粥样硬化与冠心病有相关性。Aim To know about the incidence rate of carotid atherosclerosis of the patients with coronary heart disease; To analyze the related risk factors of carotid atherosclerosis of the patients with coronary heart disease; To determine the relationship between the aggravation of carotid atherosclerosis and coronary atherosclerosis; To summarize the pathologic character of carotid atherosclerosis of the patients with various coronary heart disease. Methods Review the result of coronary angiography and carotid ultrasound and the related risk factors of the patients who were diagnosed as coronary heart disease through coronary angiography. The patients were divided into the carotidatherosclerosis group and the non-carotidatherosclerosis group. The patients were divided into stable angina pectoris （AP） group, unstable angina pectoris （UAP） group and acute myocardial infaction （AMI） group according to the diagnotic criterion of coronary heart disease of WHO. The patients were divided into group A （coronary artery of single vessel lession）, group B （ coronary artery of double vessel lession）, group C （coronary artery of triple vessel lession） and group D （left main vessel lession）. The aggravation of carotid atherosclerosis was graded. Results There were 198 patients with various aggravative carotid atherosclerosis among 228 patients with coronary heart disease （ 86. 8% ）. Carotid atherosclerosis was much related with hypertension and non-related with age, sex, body mass index （BMI）, smoking, drinking, hyperlipidermia, hyperuricermia and diabetes mellitus. The aggravation of carotid atherosclerosis got graver with the severity of coronary atherosclerosis. But only the plaque number of group A was more than group D （P 〈 0.05）. The grading integral and Crouseintegral of carotid atherosclerosis of AP group was not remarkablely less than UAP group. The grading integral of carotid atherosclerosis of AP group was less than AMI group and the Crouse integral of AP group was more. But there w

关 键 词：冠心病 颈动脉粥样硬化 冠状动脉粥样硬化 

分 类 号：R5[医药卫生—内科学]