妊娠期高血压疾病与血钙水平的相关性研究  

The correlation between serum calcium level and hypertensive disorder complicating pregnancy

作　　者：杨升[1] 谭剑平[2] 陈宏霞[1] 郭仲杰[2] 张建平[2] 

机构地区：[1]中山市人民医院,广东中山528402 [2]中山大学孙逸仙纪念医院,广东广州510120

出　　处：《热带医学杂志》2011年第7期768-769,777,共3页Journal of Tropical Medicine

基　　金：广东省卫生厅医学科研立项(A2010171);广东省科技计划项目(2010B060900034)

摘　　要：目的探讨妊娠期高血压疾病与母体血清钙水平的关系。方法检测102例妊娠期高血压疾病患者产前外周血清钙含量,将100例正常晚期妊娠妇女及100例非妊娠健康妇女作为对照组进行比较。结果妊娠期高血压疾病组低钙例数为89例,占87.25%,与妊娠对照组及非妊娠对照组相比,差异有统计学意义(P<0.05)。妊娠对照组的血钙水平为(2.14±0.30)mmol/L,与非妊娠对照组相比降低,但差异无统计学意义(P>0.05);而妊娠期高血压疾病组的血钙水平为(1.87±0.28)mmol/L,与妊娠对照组及非妊娠对照组相比显著降低,差异均有统计学意义(P<0.05)。结论母体血清钙含量降低可能在妊娠期高血压疾病病理生理变化中起重要作用,在监测血钙水平的同时,可进行有针对性的钙剂治疗。Objective To explore the relationship between maternal serum calcium level and hypertensive disorder complicating pregnancy.Methods Serum calcium level of 102 cases of patients with hypertensive disorder complicating pregnancy（HDCP） were measured and compared with those of 100 cases of normal late pregnant women and 100 non-pregnant healthy women.Results 89 cases of hypocalcemia was found in HDCP,accounted for 87.25%.The serum calcium level in HDCP group was（1.87±0.28） mmol/L,and was significantly lower than normal late pregnant women [（2.14±0.30） mmol/L,P0.05].Serum calcium level of the normal late pregnant women was lower than that of the non-pregnant control group,but the difference was not significant（P0.05）.Conclusion The low serum calcium level may play an important role in the pathophysiological changes of HDCP.Monitoring of the serum calcium level and taking calcium supplement can be a targeted therapy for HDCP.

关 键 词：妊娠期高血压疾病 血钙 补钙 

分 类 号：R714.246[医药卫生—妇产科学]