表面润滑型聚乙烯醇水凝胶医用导管的力学性能研究  

Study on the mechanical properties of surface-lubricated catheter made of PVA hydrogel

作　　者：毛立江[1] 胡元洁[1] 朴东旭[1] 孙瑞焕[1] 陈晓东[1] 张颖[1] 

机构地区：[1]中国康复研究中心医用高分子研究室,北京100077

出　　处：《中国康复理论与实践》1999年第4期145-149,共5页Chinese Journal of Rehabilitation Theory and Practice

基　　金：国家科委资助

摘　　要：制备了两种高分子水凝胶弹性体构成的医用导管，考察了其力学性能。将30％wt聚乙烯醇水溶液注模后，反复冻结、缓慢解冻，得到一种水凝胶管（A）。将聚乙烯醇（30％wt）、二甲基亚砜（10％wt）和水（60％wt）加热、溶解、注模、冷却，得到另一种水凝胶管（B）。这两种水凝胶管的强度（30～40MPa）和伸度（350％～400％）均与市售的硅橡胶管和聚氯乙烯导管相仿；但是就弹性模量而言，（B）管为10MPa，与硅橡胶管相近，（A）管只有4MPa。γ-射线灭菌使这两种高分子水凝胶管的强度损失达40％～50％；而洗必太水溶液灭菌对它们的力学性能没有影响。两种水凝胶管的力学性能上的显著差异归因于PVA大分子的取向及结晶结构不同所致。Two types of catheter made of polymeric hydrogel were prepared and their mechanical properties were studied. The results showed PVA hydrogel catheter was prepared by repeated freezing-thawing cycles of PVA solution in mould. Another type of catheter (PVA-DMSO - hydrogel ) was prepared by cooling the PVA solution containing 10%wt DMSO in mould. The tensile strength (30~ 40MPa)and elongation(380 % ~400%) of these two types of catheter were comparable with those of commercial PVC catheter and silicone rubber catheter. But the elastic modulus of PVA-DMSO hydrogel catheter was 10MPa,near to silicone rubber catheter and that of PVA hydrogel catheter was only 4MPa. γ-ray irradiation for sterile made 40% ~50% loss of tensile strength for both catheter. Dipping in hibitane aqueous solution didn't affect mechanical properties.The obvious difference in mechanical properties was due to the difference in the orientation of PVA molecule chain and crystalline structure.

关 键 词：医用导管 弹性模量 应力应变 高分子材料 

分 类 号：R318.08[医药卫生—生物医学工程]