大鼠丘脑及邻近部分神经结构微血管的定量研究  

QUANTITATIVE STUDY ON THE MICROVASCULAR NETWORK OF THE RAT THALAMUS AND ADJACENT STRUCTURES

作　　者：顾少光[1] 张宝琳[1] 邓春芳[2] 焦树平[2] 

机构地区：[1]承德医学院解剖教研室 [2]哈励逊国际和平医院

出　　处：《承德医学院学报》1999年第4期297-300,共4页Journal of Chengde Medical University

摘　　要：目的:观察并定量研究大鼠丘脑及邻近部分神经结构的微血管。方法:应用血管染色法显示了40例大鼠丘脑及邻近结构的微血管;采用体视学方法对血管团边界明显的神经结构的微血管密度做定量研究,并用目镜测微器测这些结构的微血管管径;应用计算机图像分析系统测算这些结构微血管投影面积的百分比。所得数据均做统计处理。结果:核团的血管密度明显高于纤维束的血管密度(P<0.01),各核团间血管密度也有差异,前核密度最高,腹核与束旁核居中等,缰核、背内侧核、外侧核密度较低。高、中、低密度核团间均有显著性差异(P<0.01)。在各结构的微血管管径方面,缰核脚间束,缰核、外侧核的较粗,腹核最细,三者与腹核相比较均有显著性差异(P<0.01),束旁核、前核群,背内侧核与髓纹居中,四者之间以及与腹核之间无明显差异,但与缰核脚间束的差异显著(P<0.05)。各结构的微血管密度与直径之间存在负相关趋势,但无统计学意义。结论:核团的血管密度高于纤维束的血管密度,部分核团间血管密度存在差异。Objective:To observe and Quantitatively study the microvascular network of the rat thalamus.Methods:we measured quantitatively the microvascular density with a stereological method and diameter under the ocular micrometer in 8 structures which had clear masses.The area percentage of microvessels in the same structures was also measured by computer image analysis system.Results:The microvascular density in nuclei significantly higher than that in the tracts(P<0.01),and the different nuclear groups varied in density.The density in the A group was the highest,the PP and the V group the middle,the L,MD and H the lowest; there were significant difference among the three groups(P<0.01).As regards the dirameter of microvessels,the diameter in H,HPT and L was wider,and in V was the thinnest;the diameter in the three nuclei were significantly wider than that in V (P<0.05).The diameter in PF,A,SM and MD was medium in longth.The diameter in the four nuclei and HPT varied obviously(P<0.05),but there was no significant difference among the four nuclei and V in diameter.In the same measured structrues,negative correlation tendency was shown between the microvascular density and diameter,but there was no significance in statistics.Conclusion:The microvascular density in nuclei significantly higher than that in the tracts,and the different nuclear groups vary in density.

关 键 词：丘脑 血管构筑 体视学 图像分析 过氧化物酶 大鼠 

分 类 号：R322.8[医药卫生—人体解剖和组织胚胎学]