丙泊酚复合小剂量舒芬太尼用于无痛人流的疗效探讨  

Clinical effects of propofol combined with low dose sufentanil on anesthesia for artificial abortion

作　　者：安宁[1] 

机构地区：[1]崇州市人民医院麻醉科,四川611230

出　　处：《齐齐哈尔医学院学报》2011年第12期1906-1907,共2页Journal of Qiqihar Medical University

摘　　要：目的探讨丙泊酚复合小剂量舒芬太尼用于无痛人流麻醉的效果和安全性。方法选择门诊ASAⅠ～Ⅱ级自愿接受无痛人工流产的手术患者80例,随机分为观察组(S组)与对照组(K组),每组40人。S组为舒芬太尼0.1μg/kg加丙泊酚;K组为氯胺酮0.5mg/kg加丙泊酚。观察并记录两组的麻醉诱导前、意识消失后、麻醉苏醒时的HR、Bp、RR和SPO2变化,以及术中术后镇痛效果、丙泊酚总用量、手术时间、麻醉苏醒时间和离院时间。结果 S组术中术后镇痛效果均优于K组(P<0.05),且麻醉苏醒时间和离院时间也明显短于K组(P<0.05)。结论舒芬太尼复合丙泊酚用于无痛人流麻醉安全有效,优于氯胺酮复合丙泊酚。Objective To explore the efficacy and safety of low dose sufentanil combined with propofol on anesthesia for induced abortion.Methods 80 ASAⅠ~Ⅱpatients of early pregnancy with voluntarily induced abortion were randomized to observation group(Group S)and control group(Group K)(n=40).Sufentanil 0.1ug/kg combined with propofol was administered in Group S while ketamine 0.5mg/kg combined with propofol in Group K.The change of heat rate,blood pressure,breath rate and oxygen saturation were recorded during operation.Other outcome including intraoperative and postoperative analgesia effect,the total dose of propofol,operation duration,the time for emergence and leaving hospital,and adverse events,were observed.Results The intraoperative and postoperative analgesia effects in Group S were better than that in Group K(P<0.05).In addition,both the time for emergence and leaving hospital in Group S were shorter than that in Group K(P<0.05).Conclusions Propofol combined with sufentanil on induced abortion is safe and effective,and its effects are better than propofol combined with ketamine.

关 键 词：丙泊酚 舒芬太尼 氯胺酮 无痛人流 

分 类 号：R971.2[医药卫生—药品]