外周血嗜酸细胞计数在条件免疫反应哮喘动物模型的变化观察  

The observation on the changes in the counts of peripheral eosinophils of asthma animal models with conditioned immunoreaction

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作  者:张晓奇[1] 刘雅琴[2] 曾常茜[2] 王淼[2] 李玉英 

机构地区:[1]吉林医学院附属医院神经内科,吉林 132001 [2]吉林医学院免疫教研室 [3]吉林省医院电诊室

出  处:《吉林医学院学报》1999年第3期18-20,共3页

基  金:吉林省教育委员会资助项目

摘  要:目的;观察嗜酸细胞数在条件免疫反应哮喘动物模型的变化。方法:对经过条件刺激和未进行条件刺激和各组动物予以心脏采血,做血图片。Wright氏染色,放于光镜下计数。结果;CS1,CS2,NS1三组嗜酸细胞计灵敏我明显差异P〉0.05,CS3,NS2□两组嗜酸细胞计数结果无明显差异P〉0.05;CS1,CS2与CS3比较P〈0.01有显著差异;Objective:To observe the changes in the counts of eosinophils of asthma animal models with conditioned immunoreaction.Methods:Blood samples collected from the hearts of animals in CS groups and non-CS groups were smeared and stained with wright's method and then counted under light microscope.Result: There were no significant differences in eosinophils counting between CS1.CS2 and NSl groups (P>0.05).There was no significant difference betwween CS3 and NS2 (P>0.05).The difference was significant between CS1.CS2 groups and CS2 group.(P<0.01) and also between NSl and NS2.There were significant differences between CS1 CS2 NSl and CS3.NS2(P<0.01).Conclusion:The eosinophil counting does not vary with the presence or absence of CS but is associated with the times of asthma attack.

关 键 词:嗜酸细胞计数 条件免疫反应 动物模型 哮喘 

分 类 号:R562.250.2[医药卫生—呼吸系统]

 

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