杂多化合物抗伪狂犬病病毒的活性研究  

The stuty on the antipseudorabies virus activity of heteropoly acid compounds

作　　者：王丽君 姜虹 杨春梅 

机构地区：[1]吉林医学院有机化学教研室 [2]吉林医学院生化教研室

出　　处：《吉林医学院学报》1999年第3期10-11,共2页

摘　　要：目的：测定杂多化合的抗伪狂犬病病毒的活性。方法：采用细胞培养法测定杂多化合物对兔肾细胞的毒性及在无毒浓度下，抗伪狂犬病病毒的活性。结果：ＨＰＣ－１，ＨＰＣ－５，ＨＰＣ－６，ＨＰＣ－７的ＴＩ值分别为１００，１００，１０３，１０７．５结论：上述杂多化合物具有较低的毒性以及较强的抗伪狂犬病病毒的活性。Objective:To determine the Antipseudrorabies virus activity of heteropoly acid compounds.Methods:toxicities of various compounds on the cell fror rabbit kidney and antipseudvorabies virus activity of them under a non-toxic concentration were estimated by using methods of cell culture.Result:The TI valu of HPC-11,HPC-5, HPC-6,HPC-7 were 100,100,103,107.5 respectively.Conclusion:Some of the heteropoly acid compounds have significant an tipseudvorabies virus activity and lower toxicity.

关 键 词：杂多化合物 抗伪狂犬病病毒 活性 药理 

分 类 号：R978.7[医药卫生—药品]