有机磷农药中毒心律失常国内文献回顾  

Arrhythnfia induced by acute organophosphorous pesticide poisoning： a literature review

作　　者：宣丹旦[1] 郑舒聪[1] 万伟国[1] 裘昊旻[1] 邹和建[1] 

机构地区：[1]复旦大学附属华山医院职业病科,上海200040

出　　处：《中华全科医师杂志》2011年第8期569-570,共2页Chinese Journal of General Practitioners

基　　金：国家“十一五”科技支撑项目“急性职业中毒救治关键技术研究”（2006BA106801）

摘　　要：对1979至2010年国内学术期刊上发表的有机磷农药中毒心律失常文献进行统计和分析.共收集到有机磷农药中毒3468例,心电图异常率35.4%～68.4%,平均（53±15）%.最常见心电图表现为ST-T段改变（26.5%）和窦性心动过速（16.6%）.有机磷农药中毒程度越重,心电图异常例次与患者人数的比值越高,且越容易发生严重心律失常（x2=33.253,P〈0.01）,最常见死亡原因是室性心动过速和心室颤动（26.2%）.Literatures on arrhythmia induced by acute organophosphorous pesticide poisoning published in domestic journals from 1979 to 2010 were searched. Total 3468 cases of acute organophosphorous poisoning were collected and analyzed. The average abnormal ECC rate was （53 ±15）%（35. 4% -68. 4% ） in acute organophosphorous poisoning, the most common ECG abnormalities were ST-T segment changes （26. 5% ） and sinus tachycardia （16. 6% ）. The rate and severity of ECG abnormalities were increased with the severity of organophosphorous poisoning（x2 = 33. 253,P 〈 0. 01）. The most common causes of death in acute organophosphorous poisoning were ventricular tachycardia and ventricular fibrillation （26.2%）.

关 键 词：有机磷化合物 心律失常 

分 类 号：R595.4[医药卫生—内科学]