潮气呼吸肺功能测定在5岁以下支气管哮喘儿童中的应用  

Study on lung function test via tidal breathing in children under age of 5 years with bronchical asthma

作　　者：安淑华[1] 李金英[1] 张剑霄[1] 王亚坤[1] 王艳艳[1] 郑博娟[1] 

机构地区：[1]河北省儿童医院呼吸心内科,石家庄050031

出　　处：《疑难病杂志》2011年第8期583-585,共3页Chinese Journal of Difficult and Complicated Cases

基　　金：河北省医学适用技术跟踪项目(No.GL200841)

摘　　要：目的探讨潮气呼吸肺功能测定在5岁以下哮喘患儿中的应用价值。方法对20例5岁以下儿童分别于哮喘急性期及缓解期行潮气呼吸肺功能测定,比较治疗前后肺功能指标变化。并与20例健康儿童进行对照。结果 (1)与健康对照组比较,急性期组VT/kg、TPTEF/TE、VPEF/VE、Ti/Te、TEF25%、TEF50%均较低,Rr升高(P<0.05),余指标差异无统计学意义(P>0.05);(2)与健康对照组比较,缓解期组TPTEF/TE VPEF/VE、TEF50%、TEF25%有所恢复,但仍较低(P<0.05),余指标差异无统计学意义(P>0.05);(3)与急性期组比较,缓解期组VT/kg、Ti/Te、TPTEF/TE、VPEF/VE均升高(P<0.05),余指标差异无统计学意义(P>0.05)。结论潮气呼吸肺功能检查对评估5岁以下哮喘儿童气道功能改变具有一定的参考价值。Objective To investigate the changes in large and small airway function of asthmatic children under age of 5 years by comparison of the lung function index of tidal breathing changes pre and post regular treatment.Methods Twenty asthmatic children under age of 5 years who were measured with tidal flow volume curve function test pre and post treatment,with 20 healthy children were enrolled as control.Results（1） Comparison to healthy children,the index of large airway function including VT/kg,TPTEF/TE,VPEF/VE,Ti/Te,TEF25%,TEF50%in asthmatic children were significantly improved in acute stage,while the indexes were still lower than those in healthy children,Rr was higher than healthy children （P 0.05）.There was no statistical significance in other indexes（P 0.05）.（2） The indexes of TPTEF/TE,VPEF/VE, TEF50%,and TEF25%in asthmatic children were improved in recovery stage,while still lower than those in healthy children （P 0.05）.There was no statistical significance in other indexes（P 0.05）.（3） Comparison to acute stage,the indexes of VT/kg,Ti/Te,TPTEF/TE,VPEF/VE in asthmatic children were improved（P 0.05）,while no statistical difference in other indexes（P 0.05 ）.Conclusion It demonstrated the value of lung function test via tidal breathing in evaluating airway function of asthmatic children under age of 5 years old.

关 键 词：支气管哮喘 潮气呼吸肺功能 小气道功能 大气道功能 儿童 <5岁 

分 类 号：R725.6[医药卫生—儿科]