脑源性神经营养因子在缺氧缺血性脑病中脑保护作用的研究进展  

The Protective Function of Brain-derived Neurotrophic Factor in Hypoxic-ischemic Encephalopathy

作　　者：王雪[1] 何平[1] 

机构地区：[1]昆明医学院第二附属医院儿科,云南昆明650000

出　　处：《中国现代医生》2011年第23期30-31,42,共3页China Modern Doctor

摘　　要：缺氧缺血性脑病是围生期新生儿常见的危急重症,且在存活者中神经系统后遗症的发生率也比较高,其一直以来都受到研究学者的广泛关注。近年来研究表明,脑源性神经营养因子在缺氧缺血性脑病中有积极的对抗脑损伤的作用。本文现就脑源性神经营养因子的结构、功能、可能的作用机制做如下综述。The hypoxic-ischemic encephalopatuy （ HIE ） is newborn＇s common critical disease, and the rate of nervous system＇ s sequela is quite high,so it has always been widely concerned by scholars .In recent years, studies show that brain-derived neurotrophic factor has the protective function that can resist the brain damage in HIE. This article is a summary on BDNF＇ s structure, function, possible mechanism.

关 键 词：缺氧缺血性脑病 脑源性神经营养因子 

分 类 号：R722.1[医药卫生—儿科]