金芍胶囊挥发油类成分提取工艺探讨  

Discussion on Extraction Process of Volatile Oil Extraction from Jinshao Capsule with Orthogonal Design

作　　者：蒋东旭[1,2] 王德杭[2] 黄有带 景运条 赖小平[1,2] 

机构地区：[1]东莞广州中医药大学中医药数理工程研究院,广东东莞523808 [2]广州中医药大学,广州510006 [3]广东德鑫制药有限公司,广东江门529100

出　　处：《中国实验方剂学杂志》2011年第16期13-15,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广东省社会发展计划项目(2009A030100001)

摘　　要：目的:确定金芍胶囊中挥发油类成分的提取工艺并优化工艺参数。方法:对比超临界CO2萃取法与水蒸气蒸馏法对提取金芍胶囊中挥发油类成分的影响,探讨产业化实施中可能产生的问题,对可行工艺的参数进行优化。结果:采用超临界CO2萃取法萃取金芍胶囊中挥发油类成分,产品稳定性符合相关规定。结论:超临界CO2萃取法,无污染,选择性高,适用于金芍胶囊工业化生产。Objective：To determine the volatile oil extraction technology of Jinshao capsule and to optimize process parameters.Method：Compared the volatile oils ingredient influence in Jinshao capsule by the way of supercritical CO2 extraction and steam distillation,discussed the problem in industrialized implementation,Optimized parameters of feasible technology.Result：The volatile oil was obtained from Jinshao capsule by Supercritical CO2 extraction.The product stability conforms to the related stipulation.Conclusion：This method is non-pollution,which has high selectivity,also suitable for industrial production.

关 键 词：超临界CO2萃取法 金芍胶囊 水蒸气蒸馏法 

分 类 号：R283.6[医药卫生—中药学]