个体化肝素盐水封管在血液透析患者中心静脉留置导管中的应用  

Application of individualized heparinized saline to seal tube to indwelling central venous catheter for hemodialysis patients

作　　者：潘红[1] 王雪梅[1] 王钰君[1] 谢兆媛[1] 

机构地区：[1]山东大学附属省立医院,山东济南250021

出　　处：《齐鲁护理杂志（下旬刊）》2011年第7期3-4,共2页Journal of Qilu Nursing

摘　　要：目的:探讨个体化肝素盐水封管在血液透析患者中心静脉留置导管中的应用效果。方法:将100例采用中心静脉置管行血液透析患者随机分为观察组和对照组各50例,对照组采用2 100 U/ml肝素盐水封管液,观察组采用个体化肝素盐水封管液,比较两组导管留置时间、凝血指标及导管内血栓、置管处渗血、导管相关性感染发生率。结果:观察组导管留置时间平均为(28.0±5.2)d,对照组平均为(27.0±3.5)d,两组比较差异无统计学意义(P>0.05)。两组在凝血指标、置管处渗血、导管相关性感染方面比较差异无统计学意义(P>0.05);观察组导管内血栓形成发生率低于对照组(P<0.05)。结论:在血液透析患者中心静脉留置导管中应用个体化肝素盐水封管,可降低血栓发生率,减少插管部位出血,降低医疗费用,值得推广使用。Objective： To investigate the application effect of individualized heparinized saline to seal tube to indwelling central venous catheter for hemodialysis patients.Methods： 100 hemodialysis patients with central venous catheterization were randomly divided into an observation group and a control group（50 patients for each group）.2 100 U / ml heparin saline sealing solution was used in the control group and the individualized heparinized sealing solution was used in the observation group.The indwelling time of the catheter,coagulation and thrombosis in the catheter lumen,oozing at the puncture point and the incidence of catheter-related infections were compared between the two groups.Results： The average indwelling time of the catheter was（28.0±5.2） days in the observation group and（27.0±3.5） in the control group,the difference was not statistically significant between the two groups（P0.05）.There were not statistically significant differences in the comparison of coagulation and thrombosis in the catheter lumen,oozing at the puncture point and the incidence of catheter-related infections between the two groups（P0.05）;the incidence of thrombosis in the catheter lumen is lower in the observation group than that in the control group（P0.05）.Conclusion： The individualized heparinized saline used to seal tube can reduce the incidence of thrombosis,bleeding at the puncture point and hospitalization expenses of the hemodialysis patients with central venous catheterization.

关 键 词：个体化肝素盐水封管 中心静脉置管 血液透析 

分 类 号：R473.5[医药卫生—护理学]