2-双烷硫基亚甲基-5,5-二甲基-1,3-环己二酮与Grignard试剂加成反应取向的初步研究  

Preliminary studies on the addition orientation of 2-dialkylthiomethylene-5, 5-dimethyl-1, 3-cyclohexadione with Grignard reagents

作　　者：方群欣[1] 宁波[2] 胡玉兰 赵保中[1] 刘群[1] 

机构地区：[1]东北师范大学化学学院,吉林长春130024 [2]长春市轻工业学校,吉林长春130021

出　　处：《东北师大学报（自然科学版）》1999年第4期44-47,共4页Journal of Northeast Normal University(Natural Science Edition)

基　　金：国家教委优秀年轻教师基金

摘　　要：用具有不同烷硫基的2－双烷硫基亚甲基－5，5－二甲基－1，3－环已二酮与烯丙基、2－甲基烯丙基、苯基卤化镁等Grignard试剂反应，对加成反应取向进行了初步考察．2－双烷流基亚甲基－5，5－二甲基－1，3－环已二酮与烯丙基和2－甲基烯丙基的加成均得到1，2－加成产物；2－二甲硫基亚甲基－5，5－二甲基－1，3－环已二酮与苯基溴化镁反应可得1，4－加成产物．The orientation on the addition reaction of 2 - dialkythiomethylene - 5, 5 -dimethyl - 1, 3 - cyclohexadione - which with the different dialkylthio group enclonding dimethylthio, 1, 2 - ethylenedithio and 1, 3 - propylidenedithio - with Grignard reagents was studied preliminarily. The results for the addition showd that the orientation is similar as the common α - oxo ketene dithioacetals. 1, 2 - addition preducts were obtained with allyl and methyllyl Grignard reqents to the different dialkylthio groups. An 1,4 - addition product was prepared when 2 - dimethylthio methylene - 5, 5 - dimethy 1 - 1, 3- cyclohexadione reacts with phenyl Grignard reagent.

关 键 词：二甲基 环己二酮 GRIGNARD试剂 加成反应 

分 类 号：O624.42[理学—有机化学]