原发性骨质疏松症综合治疗的临床研究  

The Clinical Study of Drug Comprehensive Treatment in Primary Osteoporosis

作　　者：侯林俊[1] 孔祥录[1] 朱治国[1] 盖伟[1] 于远洋[1] 崔成亮[1] 杨勇[1] 

机构地区：[1]首都医科大学燕京医学院附属良乡医院,102400

出　　处：《首都医药》2011年第16期37-38,共2页Capital Medicine

摘　　要：目的应用综合药物治疗方案结合运动锻炼来治疗原发性骨质疏松症,观察其疗效。方法对543例原发性骨质疏松症患者按能否接受系统药物治疗分为治疗组(鲑鱼降钙素鼻喷剂+阿法D3钙剂组)和对照组(单纯阿法D3钙剂组),两组再根据能否长期坚持运动锻炼再分为运动组和非运动组两个亚组,疗程12个月。治疗结束后,观察骨密度变化情况、疼痛改善情况以及骨折率。结果 "综合药物+运动组"的骨密度增加程度和疼痛改善率明显高于"对照疗法+非运动组",骨折率明显低于"对照疗法+非运动组"。结论综合药物治疗方案可提高骨密度、改善疼痛,运动锻炼可提高骨质量,增加骨强度,从而降低骨折风险,提高患者生活质量,效果满意。Objective To study the effect of drug omprehensive treatment combined with exercise in osteoporosis.Methods 543 patients with primary osteoporosis were divided into treatment group（salmon calcitonin nasal spray ＋αD3＋calcium）and control group（singleαD3＋calcium）.According to whether the long-term adherence of exercise,then,the two groups divided into two subgroups of exercise group and non-exercise group.After 12 months of treatment,observed the changes of BMD,pain and fracture rate.Results As for the increase extent of BMD and pain improvement,Drug ＋ exercise group was significantly higher than the control treatment ＋ non-exercise group,the fracture rate was significantly lower than the control treatment ＋ non-exercise group.Conclusion Comprehensive drug treatment program can improve bone density,improve pain,exercise can improve bone mass and increase bone strength,thereby reducing fracture risk,improve patient quality of life,results were satisfactory.

关 键 词：骨质疏松 综合治疗 运动 

分 类 号：R68[医药卫生—骨科学]