硝酸铈对大鼠组织中ATP酶活性的影响  

Effect of cerous nitrate on the activity of ATPase in tissues

作　　者：杨维东[1] 王艇[2] 雷衡毅 杨燕生 

机构地区：[1]暨南大学生物工程系,广州510632 [2]中山大学生命科学学院

出　　处：《卫生研究》1999年第6期329-330,355,共3页Journal of Hygiene Research

基　　金：国家自然科学基金;广东省自然科学基金

摘　　要：研究了硝酸铈对大鼠内脏、大脑、肌肉中ＡＴＰ酶活性的影响。结果显示，连续腹腔注射低浓度硝酸铈后，大鼠肝脏、肾脏、心脏等组织中Ｃａ２＋ －ＡＴＰ酶，Ｋ＋ 、Ｎａ＋ －ＡＴＰ酶，Ｍｇ２＋ －ＡＴＰ酶活性明显增强；而当注射高浓度硝酸铈时，酶活性均未发生明显变化。The effect of cerous nitrate on the activity of some ion dependent ATPase such as Ca 2+ -ATPase, K +,Na +-ATPase and Mg 2+ -ATPase was studied in vivo. The results showed that Ca 2+ -ATPase, K +,Na +-ATPase and Mg 2+ -ATPase activity was increased in rat liver, kidney and heart after recurrent intraperitoneal administration of low dose of cerous nitrate(1mg/kg),but no changes happened for these enzymes activity after high cerous nitrate administration(50mg/kg).The mechanism of the phenomena was discussed.

关 键 词：铈 ATP酶 大鼠 硝酸铈 

分 类 号：Q557[生物学—生物化学] O614.332[理学—无机化学]