外科加强医疗病区耐甲氧西林金黄色葡萄球菌感染的分析  

Analysis of Methicillin Resistant Staphylococcus Aureus Infection in Surgical Intensive Care Unit

作　　者：陈敏英[1] 林志华[1] 管向东[1] 欧阳彬[1] 陈娟[1] 

机构地区：[1]中山医科大学附属第一医院外科加强医疗病区,广州510080

出　　处：《中山医科大学学报》1999年第4期293-295,共3页Academic Journal of Sun Yat-sen University of Medical Sciences

摘　　要：通过分析我院外科加强医疗病区(SICU)感染耐甲氧西林金黄色葡萄球菌(MRSA)患者的资料,总结引起MRSA感染的危险因素。方法:回顾性调查1996年1月～1998年12月入SICU的1069例患者资料,按感染细菌分为MRSA组和非MRSA组,比较两组的发病率及病死率;比较两组患者在ICU住院时间、广谱抗生素应用、血清白蛋白含量的差异,计算各因素的优势比(OR)。结果:MRSA20例,非MRSA57例,MRSA感染患者病死率为非MRSA的1.9倍,P<0.05;MRSA感染相关因素有ICU住院时间(P=003,OR=252)、广谱抗生素的应用(P=004,OR=16.10)、低白蛋白血症(P=0.01,OR=234)。结论:MRSA感染病死率高,ICU住院时间长、应用广谱抗生素、低白蛋白血症是引起MRSA感染的危险因素。Objective: To summed up the risk factors of methicillin resistant Staphylococcus aureus(MRSA) infection by analying the data of patients which infected with MRSA. Methods: Retrospectively analyzed the data of 1 069 patients in surgical intensive care unit(SICU) from 1996.1 to 1998.12,patients who had infection were divided into two groups: MRSA and non MRSA. Comparing the morbidity and the fatality and the hospitalization in ICU , the using of broad spectrum antibiotics and serum albumin value in two groups ,calculated the Odds ratio(OR). Results: Patients with MRSA were 20, with non MRSA were 57, the fatality of patients with MRSA was 1.9 times higher than that of patients with non MRSA(P<0.05),respectively; the hospitalization in ICU (P=0.03,OR=2.52),the using of broad spectrum antibiotics(P=0.04,OR=16.10) and hypoalbuminemia (P=0.01, OR=2.34) were related to MRSA infection, respectively. Conclusions: MRSA infection had high fatality, prolonged staying in ICU, using of broad spectrum antibiotics and hypoalbuminemia were the risk factors of MRSA.

关 键 词：感染 加强医疗病区 金黄色葡萄球菌 甲氧西林 

分 类 号：R631.3[医药卫生—外科学] R181.34[医药卫生—临床医学]