177例新生儿湿肺危险因素分析  

Risk factors and clinical features of 177 cases of transient tachypnea of the newborn

作　　者：求伟玲[1] 杜立中[1] 

机构地区：[1]浙江大学医学院附属儿童医院新生儿科,杭州310003

出　　处：《浙江医学》2011年第7期1040-1043,共4页Zhejiang Medical Journal

摘　　要：目的 探讨新生儿湿肺相关危险因素,研究相关危险因素与病情严重程度有无关联.方法 回顾性分析177例新生儿湿肺的临床资料,对其产科因素、出生情况、临床表现、辅助检查、治疗情况等进行统计分析,并以是否使用机械通气或持续气道正压（CPAP）治疗将患儿分为重病组及轻病组,比较两组患儿的临床情况.结果 在 177例新生儿湿肺患儿中,剖宫产占93.2%,男性患儿占74.6%,妊娠期存在并发症的占48.6%.重病组与轻病组在妊娠期并发症、胎龄、患儿出生体重、患儿气急、24h内及24～48h内最大呼吸频率方面的差异均有统计学意义（均P＜0.05）.结论 剖宫产、男性患儿、早产儿、围生期窒息可能是新生儿湿肺的危险因素,其中妊娠期存在并发症、早产儿、出生体重低可能是患儿病情严重（需行辅助通气治疗）的危险因素.Objective To investigate the risk factors of transient tachypnea of the newborn （TTN）, and their relationship with the disease severity. Methods The clinical data of 177 patients with -TTN were retrospectively analyzed. Obstetric factors and clinical findings were compared between patients receiving mechanical ventilation or continuous positive airway pressure （CPAP） （group 1） and those not receiving mechanical ventilation or CPAP （group 2）. Results In 177 patients with TTN, 93.2% were delivered by Cesarean section, 74.6% were male gender, 48.6% born to mothers with pregnancy complications. There were significant differences between group 1 and group 2 in terms of the pregnancy complications, gestation age, birth weight of the newborn, tachypnea,the peak respiratory rate in 24h, and 24h - 48h （all P〈 0.05）. Conclusion Cesarean delivery, male gender, pregnancy complications, preterm infants, and perinatal asphyxia may be risk factors of TTN Pregnancy complications, preterm infants, and low birth weight may be associated with severe TTN requiring assistant ventilation.

关 键 词：新生儿湿肺 危险因素 病情 

分 类 号：R587.1[医药卫生—内分泌]