西洋参多糖PPQI-1～4理化性质的研究  

PHYSICAL AND CHEMICAL PROPERTIES OF POLYSACCHARIDES PPQI 1～4 FROM PANAX QUIQUEFOLIUM

作　　者：马秀俐[1] 郝春艳[2] 李耀先[1] 孙允秀[1] 刘举正[1] 刘树莹 

机构地区：[1]吉林大学化学系 [2]中科院长春应化所,长春130022

出　　处：《药学学报》1999年第12期946-948,共3页Acta Pharmaceutica Sinica

摘　　要：AIM: To study the characteristics of the four bioactive pure polysaccharides of Panax quiquefolium L. (PPQI 1～4). METHODS: The polysaccharides were extracted with hot water and grade precipitated with ethanol. They were further purified with Sephadex DEAE A50 and Sephadex G200 chromatography. The molecular weights of the polysaccharides were determined with matrix assisted laser desorption/ionization mass spectrometry (MALDI MS). The sugar compositions were analyzed with GC. The linkage positions of the component sugars were determined by methylation and GC MS. RESULTS: The four polysaccharides are all uronic acid containing heteropolysaccharides with the component sugars of arabinose, galactose and glucose in different molar ratios. The uronic acid contents are within 30%～60%. Their molecular weights are in the range of 2×10 4～7×10 4 u. CONCLUSION: The four new bioactive polysaccharides are all uronic acid containing heteropolysaccharides.AIM: To study the characteristics of the four bioactive pure polysaccharides of Panax quiquefolium L. (PPQI 1～4). METHODS: The polysaccharides were extracted with hot water and grade precipitated with ethanol. They were further purified with Sephadex DEAE A50 and Sephadex G200 chromatography. The molecular weights of the polysaccharides were determined with matrix assisted laser desorption/ionization mass spectrometry (MALDI MS). The sugar compositions were analyzed with GC. The linkage positions of the component sugars were determined by methylation and GC MS. RESULTS: The four polysaccharides are all uronic acid containing heteropolysaccharides with the component sugars of arabinose, galactose and glucose in different molar ratios. The uronic acid contents are within 30%～60%. Their molecular weights are in the range of 2×10 4～7×10 4 u. CONCLUSION: The four new bioactive polysaccharides are all uronic acid containing heteropolysaccharides.

关 键 词：西洋参多糖 PPQI-1-4 理化性质 

分 类 号：R931.71[医药卫生—生药学]