2型糖尿病慢性并发症中医证候特点分析  

Characteristics of TCM Syndromes of Chronic Complications of Type Ⅱ Diabetes

作　　者：张智龙[1] 陈宏[1] 吉学群[1] 薛莉[1] 宫军[1] 王春梅[1] 

机构地区：[1]天津市中医药研究院附属医院针灸科

出　　处：《中医杂志》2011年第16期1379-1382,1386,共5页Journal of Traditional Chinese Medicine

摘　　要：目的探讨2型糖尿病慢性并发症的中医证候分布特点。方法搜集162例2型糖尿病慢性并发症患者的基本信息、中医四诊及辅助检查信息,采用因子分析、聚类分析和Logistic回归分析方法对2型糖尿病慢性并发症中医证候进行初步客观化分析。结果经因子分析后,可获得15个基本符合中医证候诊断的公因子;以症状和体征为自变量通过聚类分析,将162例患者的中医证候分为5类;采用二分类Logistic回归分析方法最终确定了各类别的证候模型。结论经过多元统计分析方法可将2型糖尿病慢性并发症的证候归为5大类,即痰湿血瘀证,气阴两虚证,脾虚湿盛证,阴虚热盛证,阴阳两虚、血瘀水停证。Objective To study the characteristics of TCM syndromes of chronic complications of type Ⅱ diabetes.Methods The basic information,TCM four diagnostic information,and accessory examination information of 162 type Ⅱ diabetes patients with chronic complications were collected.The TCM syndromes of these complications were objectively studied with factor analysis,cluster analysis,and Logistic regression analysis.Results Through the factor analysis,15 common factors basically accorded with TCM syndrome diagnosis were obtained.With the cluster analysis,taking the symptoms and signs as the independent variables,the TCM syndromes of the 162 patients were classified into 5 types.From the binary classification Logistic regression analysis,all syndrome models were confirmed finally.Conclusion By using the multiple statistical analyzing methods,the TCM syndromes of chronic complications of type Ⅱ diabetes are attributed to 5 types,namely,phlegm damp blood stasis,qi and yin both deficiency,spleen deficiency phlegm abundance,yin deficiency heat abundance,as well as yin and yang both deficiency with blood stasis water retention.

关 键 词：2型糖尿病 糖尿病并发症 中医证候 因子分析 聚类分析 LOGISTIC回归分析 

分 类 号：R259[医药卫生—中西医结合]