缺血性中风发病节律探讨  

Research on temporal variation in the occurrence of ischemic stroke

作　　者：吴文辉[1] 余兰仙[1] 叶美颜[1] 

机构地区：[1]浙江省中医院,浙江杭州310006

出　　处：《中华中医药学刊》2011年第8期1907-1909,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的：探讨缺血性中风发病的时间规律,从时间医学的角度为临床防治提供科学依据。方法：对2005年-2006年3987例新缺血性中风患者登记资料作圆形分布统计。发病时点化为角度坐标,确定缺血性中风的发病高峰时点;再以入院日期为基础,推测缺血性中风发病的季节高峰期。结果：缺血性中风患者的发病时间在06∶00~10∶00时间段有明显集中趋势,发病月份存在集中趋势,平均发病时间为1月11日±3月6日。结论：缺血性中风发病有显著季节和时辰周期规律,更好地了解这些效应有望为卒中预防制定有效策略。Objective：To explore the temporal regular pattern of ischemic stroke（IS）,provide scientific evidence for clinical on the base of chronomedicine.Methods：Circular distribution statistical method were performed on registered cases of stroke between 2005 and 2006,the points of stroke onset were transformed into angular coordinate,analyse the daily acrophase of IS incidence.We both presume the seasonal peak of IS on the base of admission date.Results：A predominant peak occurred during 6am to 10am in IS patients.Similar patterns were observed across months of the year,the average disease time was January 11th±3months and 6 days.Conclusion：There were significant seasonal variation and circadian rhythm in IS incidence.Better understanding of these effects may shed light on effective strategies for stroke prevention.

关 键 词：缺血性中风 昼夜节律 季节变化 圆形分布统计 

分 类 号：R255.2[医药卫生—中医内科学]