血液灌流治疗急性有机磷农药中毒的疗效观察  

Effects of Hemoperfusion in Patients with Organophosphorus Pesticides Poisoning

作　　者：胡杰[1] 闫敏[1] 

机构地区：[1]阜阳市人民医院急诊科,安徽阜阳236004

出　　处：《辽宁医学院学报》2011年第4期319-320,336,共3页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：目的应用血液灌流治疗急性有机磷农药中毒,观察其临床效果。方法 78例急性有机磷农药中毒患者随机分为两组。治疗组41例,在其他综合治疗的基础上及时行床边血液灌流治疗,对照组37例行常规综合治疗,观察血胆硷酯酶恢复的时间、中间综合征的发生率、住院时间、住院费用及生存率。结果治疗组血胆碱酯酶恢复正常时间显著短于对照组(P<0.05),治疗组IMS发生率及住院费用均较低(P<0.05),治疗组的治愈率显著高于对照组(P<0.05)。结论血液灌流治疗急性有机磷农药中毒疗效显著。Objectives To explore the clinical effect of hemoperfusion on the treatment of acute organophosphorus pesticides poisoning. Methods 78 patients with AOPP were randomly divided into two groups. There were 41 patients in treatment group, and they were treated with hemoperfusion on the basis of other basic medical therapies. The change of choline esterase and the therapeutic effects were observed, in comparison with control group of 37 patients, who were treated by traditional medical therapies. The comparison was made in terms of such aspects as the recovering time of CHE, IMS rate, time of hospital stay, survival rate, and hospital fees. Results In comparison, treatment group had quicker CHE recovering time, lower IMS formation rate, shorter time in hospital, higher survival rate, and fewer hospital fees than control group. Conclusion Hemoperfusion is an effective therapy to cure the patients with acute medical poisoning.

关 键 词：血液灌流 急性中毒 有机磷农药 中间综合症 

分 类 号：R139[医药卫生—劳动卫生]