白塞氏病患者人类白细胞抗原亚型及免疫球蛋白D的临床分析  

Clinical analysis on the human leukocyte antigen subtype and immunoglobulin D in Behcet's disease patients

作　　者：郭江涛[1] 曹旭晴[1] 马晓莉[1] 曹丽[1] 李红梅[1] 

机构地区：[1]宁夏自治区人民医院,宁夏银川750021

出　　处：《宁夏医学杂志》2011年第8期723-724,共2页Ningxia Medical Journal

基　　金：宁夏自然科学资助项目(2009232)

摘　　要：目的探讨白塞氏病患者(BD)人类白细胞抗原亚型分类及免疫球蛋白D(IgD)的表达。方法对102例BD患者临床资料进行回顾性分析。结果①HLA-B51阳性29例,阳性率56.9%。②IgD阳性89例,阳性率15.7%。③恶性肿瘤5例,检出率8.5%,均为女性。结论和BD发病相关联的HLA-B51检查具有重要的临床意义。对于BD合并妇科癌症的高发病率,是否是受到BD的影响,还是各种药物的影响,今后有必要做进一步的探讨研究。Objective To analyze the human leukocyte antigen subtype and immunoglobulin D（IgD） expression in Behcet＇s disease（BD） patients.Methods The clinical data of 102 patients with BD were retrospectively analyzed.Results HLA-B51 positive rate was in 29 cases（56.9%）;IgD was positive in 89 patients（15.7%）;The severe complications of cancer were occurred in 5 female cases（8.5%）.Conclusion The incidence of BD and HLA-B51 associated check has important clinical significance.BD incidence is high in gynecological cancer.

关 键 词：白塞氏病 人类白细胞抗原 免疫球蛋白D 

分 类 号：R597.9[医药卫生—内科学]