108例新型甲型H1N1流感患者初诊实验室检测结果分析  

The experimental test and analysis of 108 cases of patients with preliminary diagnosis of novel Influenza A H1N1

作　　者：黄美群[1] 郑卫东[1] 方伟[1] 罗燕飞[1] 罗盈[1] 

机构地区：[1]广东省人民医院检验科,广州510080

出　　处：《国际检验医学杂志》2011年第13期1419-1420,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨新型甲型H1N1流感患者初诊实验室检测结果的特征。方法收集该院2009年12月至2010年3月108例新型甲型H1N1流感患者(核酸阳性)和34例季节性流感患者(核酸阴性)初诊实验室检测结果,并利用SPSS13.0软件对其进行统计分析。结果 108例新型甲型H1N1流感患者中,86.1%的患者外周血白细胞总数正常,11.1%的患者偏低,只有2.78%的患者偏高;36.1%的患者淋巴细胞计数低于正常值下限;7.4%的患者单核细胞、28.7%患者嗜碱性粒细胞计数值高于正常值上限。肝功酶类指标的检测结果分别为丙氨酸氨基转移酶(ALT)23.1%的患者、天门冬氨酸氨基转移酶(AST)20.3%的患者、γ-谷氨酰基转肽酶(GGT)22.2%的患者高于正常值上限。结论分析新型甲型H1N1流感患者初诊时实验室检测结果的特征,有助于提高临床医生对本病流行特点以及首诊发热患者的监测和实验室检测结果特征的认识。Objective To characterize the preliminary diagnosis of the patients are infected with influenza A（H1N1）.Methods 108 patients with influenza A（H1N1）（nucleic acid positive） and 34 patients with seasonal influenza（nucleic acid negative） by preliminary diagnosis were studied who were collected in our hospital during December of 2009 to March of 2010.SPSS13.0 software were used to analyze the results.Results In 108 patients with influenza A（H1N1）,who had normal level of peripheral blood leucocytes accounted for 86.1%（93/108）,about 11.1%（12/108） were lower and only 2.78%（3/108） were higher.lymphocyte count below the lower limits of normal were about 36.1%,7.4% of monocyte and 28.7% of basophile granulocyte count were higher than the upper normal limit.23.1%（25/108） ALT,20.3%（22/108） AST and 22.2%（24/108） GGT were higher than the upper normal limit.Conclusion Compared with seasonal influenza patients,the group with influenza A（H1N1） had lower lymphocyte count,higher basophile granulocyte count,alanine aminotransferase（ALT）,aspartate aminotransferase（AST） and γ-glutamic GTP（GGT）.There had significant differences between these two groups.

关 键 词：流感病毒A型 H1N1亚型 初诊 实验室检测 统计分析 

分 类 号：R446.1[医药卫生—诊断学]