超声辐射下几种腙类化合物的合成研究  

Synthesis of several hydrazone derivatives under ultrasound irradiation

作　　者：阿布拉江.克依木 

机构地区：[1]新疆大学化学化工学院,新疆乌鲁木齐830046

出　　处：《化学研究与应用》2011年第8期1078-1082,共5页Chemical Research and Application

基　　金：新疆维吾尔自治区自然科学基金资助项目(2009211A02)

摘　　要：以乙酰丙酮为起始原料,经三步反应制得了ω-溴代-1-苯基-5-甲基吡唑-4-乙酮(5)。中间体5在超声波辐射下与芳基乙酮缩氨基硫脲类化合物(1a-1g)反应生成了新型的N-(1-芳基乙酮)-N'-[(1-苯基-5-甲基吡唑-4-基)噻唑-2-基]腙(6a-6g)。以1H NMR,IR,MS和元素分析对产物进行了确证及表征。ω-Bromo-1-phenyl-5-methyl-pyrazol-4-ethanone（5）was obtained from pentane-1,3-dione via multi-step reaction.Then,the target products 6a-6g were synthesized through the reaction of intermediate 5 with the arylacetonehydrazones under ultrasound irradiation.The structures of all products were determined by using 1H NMR,MS,IR spectra and elemental analysis.

关 键 词：吡唑 噻唑 腙 超声辐射 合成 

分 类 号：O626.1[理学—有机化学]