2008年三门峡市大骨节病病情监测结果分析  

Outcome analysis of Kaschin-Beck disease Monitoring in Sanmenxia City in 2008

作　　者：雒进才[1] 吴彦领[1] 

机构地区：[1]三门峡市疾病预防控制中心地方病防治所,河南三门峡472000

出　　处：《河南预防医学杂志》2011年第4期253-255,260,共4页Henan Journal of Preventive Medicine

基　　金：中央补助地方公共卫生专项资金地方病防治项目(2007)

摘　　要：目的了解三门峡市大骨节病病情现状,为大骨节病防治提供依据。方法按照国家及河南省《2007年地方病防治项目技术实施方案》的要求,2008年在三门峡市大骨节病病区选择地形、地貌、生产及生活方式上具有代表性的陕县张村乡窑店、庙洼村,灵宝市朱阳镇朱阳村进行7～12岁儿童大骨节病临床调查,同时拍右手X线片、采集部分儿童发样和当地粮样。儿童发硒、粮食硒测定采用23,一二氨基萘荧光法。在灵宝市、渑池县、陕县、卢氏县大骨节病病区乡进行16岁以上成人大骨节病病情调查。结果共检查7～12岁儿童190人,未检出大骨节病临床病例;拍摄右手X线片190人,X线阳性3人,检出率为1.58%(3/190)。共调查16岁及以上的常住人口16 222人,大骨节病临床检出率为6.65%(1 079/16 222),其中I度为4.46%(723/16 222),Ⅱ度为1.82%(295/16 222),Ⅲ度为0.38%(61/16 222)。儿童发硒平均值为(0.319±0.128)mg/kg,粮食硒平均值为(0.031±0.009)mg/kg。结论三门峡市儿童大骨节病病情已基本控制,成人大骨节病病情较为严重,应继续开展病情监测,加强对成人大骨节病的防治工作,特别是要加强以治疗现患病人为目的的二级预防。Objective To underst and Kaschin-Beck disease（KBD） status in Sanmenxia City and provide the basis for the further prevention and treatment of KBD.Methods According to The National and Henan Province Technical Scheme for Endemic Disease Control in 2007,Children aged 7 to 12 in 3 villages（Yaodian,Miaowa and Zhuyang） with the same environment such as topography,physiognomy,production mode and living habits in Shan County and Lingbao City were selected to undertake KBD clinical examination in 2008.X-ray examination of nght hand and child hair samples and food samples were coileeted to determine the content of selenium.Selenium was determined using 2,3-Diaminonaphthalene method.Adults who were 16 years or older in 5 counties（Lingbao,Mianchi,Shan and Lushi） were selected and examined for KBD.Results One hundred and ninty aged children 7 to 12 were clinically examined and clinical KBD were found,Whereas 3 children were diagnosed as KBD by X-ray examination,the positive rate was 1.58 %（3/190）.All 16222 adults were clinically examined and KBD prevelance rate was（6.65 %,1079/16 222）,including degree I（4.46 %,723/16 222）,degree II（1.82 %,295/16 222）,degreeⅢ（0.38 %,61/16 222）.The average selenium contents samples in hair and food samples were（0.319±0.128）mg/kg and（0.031±0.009）mg/kg,respectively.Conclusions Although KBD in children have been controlled in Sanmenxia City.It is still compare serious in adults.So the monitoring of KBD should be carried on and prevention and control for KBD in adults should strengthened.,which especially suggested that secondary prevention with the objective of clinically treating KBD patients should be strengthened.

关 键 词：大骨节病 流行病学 监测评价 

分 类 号：R181.32[医药卫生—流行病学]