三种肾上腺疾病相关性低钾血症138例临床分析  

Clinical analysis of 138 cases of hypopotassaemia associated with three adrenal diseases

作　　者：曹颖[1] 刘玉平[2] 李正勇[3] 

机构地区：[1]成都市第一人民医院内分泌科,成都610000 [2]四川大学华西医院内分泌科 [3]成都军区成都药材仓库

出　　处：《西南国防医药》2011年第8期853-855,共3页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的探讨三种肾上腺疾病低钾血症的发生率与诊断、治疗措施。方法对138例肾上腺疾病引起的低钾血症进行回顾性分析。结果 138例中89例原发性醛固酮增多症引起,平均血钾水平(2.8±0.6)mmol/L,低血钾发生率为97.0%;46例由库兴综合征引起,平均血钾水平(2.94±0.48)mmol/L,低血钾发生率为55.0%;3例由嗜铬细胞瘤引起,平均血钾水平(3.28±0.09)mmol/L,低血钾发生率为16.0%。结论临床上肾上腺疾病可表现为低钾血症,若只单纯补钾往往会延误病情,应有的放矢地对原发病进行治疗。Objective To study the incidence of hypopotassaemia caused by three adrenal diseases,and to explore its diagnostic and remedial measures.Methods Retrospective analysis was conducted in 138 patients with primary hyperaldosteronism/Cushing＇s snydrome/pheochromocytoma.All of them had hypopotassaemia that was corrected more or less following the surgery.Results Among 138 cases,89 cases of primary hyperaldosteronism showed a mean potassium level of（2.8±0.6） mmol/L and the incidence of hypopotassaemia was 97.0%.46 cases of Cushing＇s syndrome showed a mean potassium level of（2.94±0.48） mmol/L and the incidence of hypopotassaemia was 55.0%.3 cases of pheochromocytoma showed a mean potassium level of（3.28±0.09） mmol/L and the incidence of hypopotassaemia was 16.0%.Conclusion Adrenal diseases may be coupled with hypopotassaemia.In such cases,simple supplement of potassium is usually ineffective and even delay treatment.Etiological treatment is the right choice to control hypopotassaemia.

关 键 词：肾上腺疾病 低钾血症 原发性醛固酮增多症 库兴综合征 嗜铬细胞瘤 

分 类 号：R591.1[医药卫生—内科学]