西妥昔单抗联合FOLFIRI方案治疗转移性大肠癌病人的观察与护理  

Observation and nursing care of cetuximab combined with FOLFIRI to treat patients with metastatic colorectal cancer

作　　者：赵芳[1] 韩雪[1] 

机构地区：[1]中国医学科学院肿瘤医院

出　　处：《全科护理》2011年第22期1982-1984,共3页Chinese General Practice Nursing

摘　　要：[目的]总结西妥昔单抗联合FOLFIRI方案治疗转移性大肠癌病人的观察与护理。[方法]对19例转移性大肠癌病人行西妥昔单抗联合伊立替康(CPT-11)、氟尿嘧啶(5-FU)、亚叶酸钙(CF)组成的FOLFIRI方案治疗,同时加强心理护理、不良反应的护理等。[结果]19例病人发生胃肠道反应10例,骨髓抑制6例,粉刺样皮疹8例,延迟性腹泻4例,变态反应1例,乙酰胆碱能综合征3例,肛周脓肿1例;经过积极的预防、对症处理及护理干预,19例病人均顺利完成预定的治疗方案,无一例病人中止治疗。[结论]加强转移性大肠癌病人行西妥昔单抗联合FOLFIRI方案治疗的护理有利于治疗的顺利进行,提高治疗效果。Objective：It summarized observation and nursing care of cetuximab combined with FOLFIRI to treat patients with metastatic colorectal cancer.Methods：A total of 19 patients with metastatic colorectal cancer accepted treatment protocols of cetuximab combined with FOLFIRI were selected and obseved.At the same time,all cases were given strengthened psychological care and nursing care of adverse reactions.Results：Totally 10 patients occurred with gastrointestinal reactions,6 cases were with bone marrow suppression,8 cases were with acne-like erythra,4 cases with delayed diarrhea,1 case with allergy,3 cases with acetylcholine syndrome and 1 case with perianal abscess.By active prevention,symptomatic treatment and nursing intervention,all 19 patients had completed the scheduled treatment successfully.Conclusion：To strengthen nursing care of cetuximab combined with FOLFIRI in treatment of patients with metastatic colorectal cancer is helpful for successful treatment.And it can enhance the treatment effectiveness of them as well.

关 键 词：转移性大肠癌 西妥昔单抗 FOLFIRI方案 不良反应 护理 

分 类 号：R473.73[医药卫生—护理学]