马莲鞍化学成分研究  

Studies on the chemical consitituents in Streptocaulon griffithii Hook

作　　者：席鹏洲[1] 秦亚丽[1] 王跃虎[2] 晏永明[2] 张跃进[1] 

机构地区：[1]西北农林科技大学生命科学学院,陕西杨凌712100 [2]中国科学院昆明植物研究所,云南昆明650204

出　　处：《西北农林科技大学学报（自然科学版）》2011年第8期185-189,共5页Journal of Northwest A&F University(Natural Science Edition)

基　　金：云南省中青年学术技术带头人后备人才项目(2007PY-48)

摘　　要：【目的】研究药用植物马莲鞍（Streptocaulon griffithiiHook）全草的化学成分,以探明其药用成分。【方法】运用硅胶柱色谱、反相硅胶（RP-18）柱色谱、葡聚糖凝胶柱色谱（Sephadex LH-20）等多种方法,对萝藦科（As-clepiadaceae）马莲鞍属（Streptocaulon）马莲鞍全草中提取的化学成分进行分离纯化,并对其结构进行了分析。【结果】从马莲鞍全草中共分离得到7种化合物,经分析和鉴定,可知化合物17分别为（24S）-24-ethylcholesta-3β,5α,6β-tri-ol、7α-hydroxysitosterol-3-Oβ--glucoside、胡萝卜苷、β-谷甾醇、香草醛、4-羟基-3,5二-甲氧基苯甲醛和芳姜黄酮。【结论】从马莲鞍中分离得到的7个化合物中,化合物1、2、5、6、7为首次分离取得。【Objective】 The study explored the bioactive chemical constituents in the whole Streptocaulon griffithii Hook.【Method】 The chemical constituents of the whole S.griffithii Hook were studied with various materials isolation and identification technologies such as silica gel,RP-18,Sephadex LH-20.【Result】 The results were as follows：7 compounds were isolated from the whole S.griffithii Hook.Their structure identifications were：（24S）-24-ethylcholesta-3β,5α,6β-triol,7α-hydroxysitosterol-3-O-β-glucoside,daucosterol,β-stiosterol,isovanillin,4-hydroxy-3,5-dimethoxybenzaldehyde and arturmeron on the basis of analysis and verification.【Conclusion】 The compounds 1,2,5,6 and 7 were firstly isolated from the whole S.griffithii Hook in the 7 compounds.

关 键 词：马莲鞍 甾体 化学成分 

分 类 号：R284.1[医药卫生—中药学]