厌食症患儿唾液表皮细胞生长因子与舌苔变化关系的探讨及儿宝方的干预作用  

DISCUSSION ON RELATIONSHIP BETWEEN SALIVA EPIDERMAL GROWTH FACTOR OF ANOREXIA INFANT AND CHANGES OF TONGUE FUR AND INTERVENTION EFFECT OF ERBAO DECOCTION

作　　者：万力生[1] 罗宏英[1] 岳丽杰[1] 周少明[1] 李德发[1] 李海朋[1] 

机构地区：[1]深圳市儿童医院,深圳518026

出　　处：《中国中医药科技》2011年第4期273-273,295,共2页Chinese Journal of Traditional Medical Science and Technology

基　　金：深圳市科技和信息局资助项目No.200802064

摘　　要：目的:探讨厌食症患儿唾液表皮细胞生长因子(h-EGF)水平与舌苔厚薄的关系,观察中药儿宝方的干预作用。方法:选取厚腻苔和花剥苔厌食症患儿各30例,采用放射免疫技术测定其唾液表皮细胞生长因子(h-EGF)水平,并采用中药儿宝方治疗。结果:厌食症患儿厚腻苔组唾液h-EGF含量高,花剥苔组唾液h-EGF含量低,与正常组薄白苔组比较均有显著性差异(P<0.01);经过中药儿宝方治疗后,厚腻苔组和花剥苔组均恢复为薄白苔及薄白苔的h-EGF水平,与正常组薄白苔比较均无显著性差异(P>0.05)。结论:厌食症的发生可能与唾液表皮细胞生长因子(h-EGF)水平异常呈相关性,而中药儿宝方运脾治疗可以调节厌食症患儿唾液表皮细胞生长因子(h-EGF)水平。Objective:To discuss the relationship between anorexia infants' saliva epidermal growth factor and tongue fur changes and the intervention effect of erbao decoction.Methods:Anorexia infants of thick greasy fur and lingua geographica were selected,each group contained 30 cases.Erbao decoction was respectively given to the two group infants,The saliva epidermal growth factor was determined by radioimmunoassay.Results:The saliva epidermal growth factor level in anorexia infants of thick greasy fur was higher than that of normal,the saliva epidermal growth factor level in anorexia infants of lingua geographica was lower than that of normal,the saliva epidermal growth factor level in anorexia infants of thick greasy fur and lingua geographica recovered to the normal level after treated with erbao decoction,there was no difference between normal and anorexia infant on the saliva epidermal growth factor level.Conclusion:The occurrence of anorexia was related to the disorder of saliva epidermal growth factor level,erbao decoction could effectively treat anorexia by regulating anorexia infants' saliva epidermal growth factor.

关 键 词：厌食/中医药疗法 @儿宝方/治疗应用 唾液/分析 表皮生长因子 舌苔 人类 儿童 

分 类 号：R272[医药卫生—中医儿科学]