天津市婴儿麻疹流行特征及发病危险因素分析  

Analysis on infant measles epidemic characteristics and risk factors in Tianjin City

作　　者：丁亚兴[1] 曲江文[1] 骆晓艳[1] 田宏[1] 朱向军[1] 高志刚[1] 

机构地区：[1]天津市疾病预防控制中心免疫规划科,天津300011

出　　处：《中华疾病控制杂志》2011年第8期698-700,共3页Chinese Journal of Disease Control & Prevention

摘　　要：目的分析〈1岁组婴儿麻疹流行特征,探讨婴儿麻疹发病的危险因素。方法利用传染病疫情资料分析麻疹流行特征,病例对照研究评价麻疹院内感染状况,人群抗体水平监测资料对比不同月龄婴儿麻疹抗体水平。结果 〈1岁组病例构成比从2005年的13.92%增加到2010年的32.86%;许多婴儿在发病前7~21 d都到过医院就诊,OR=15.40,OR95%CI=6.34~37.39;260名1岁以下婴儿中抗体阳性143例,阳性率55.00%,抗体几何平均浓度（GMC）为258.38 mIU/ml,其中6~7月龄GMC只有72.16 mIU/ml,明显低于其他各组。结论院内感染和母传抗体水平降低是婴儿麻疹发病的主要危险因素。Objective To analyze the measles epidemic characteristics of less than one year old infant,and discuss the risk factors for infant.Methods The data of diseases reporting information system was used for describing the infant measles epidemic characteristics,case-control study was conducted to evaluate the situation of hospital infection,the measles antibody level of different months infant was compared with the data of antibody surveillance.Results The ratio of less than one year old group measles cases increased quickly from 13.92% in 2005 to 32.86% in 2010;it was a risk factor to go to hospital in 7～21 days before disease onset,OR=15.40（OR 95% CI=6.34～37.39）;there were 143 positive antibodies in 260 infant,the positive rate was 55.00%,the geometric mean concentration（GMC） was 258.38 mIU/ml,6～7 months GMC was 72.16 mIU/ml,significantly less than other months infant.Conclusions The risk factors of infant measles were hospital infection and the attenuation of maternal antibodies.

关 键 词：麻疹 危险因素 抗体 

分 类 号：R181.1[医药卫生—流行病学] R511.1[医药卫生—公共卫生与预防医学]