2004-2009年武汉市甲、戊型病毒性肝炎流行病学特征分析  

Analysis on epidemiological features of Hepatitis A and Hepatitis E in Wuhan City from 2004 to 2009

作　　者：孔德广[1] 罗同勇[1] 余滨[1] 胡权[1] 李秋玲[1] 杜虹[1] 王永红[1] 

机构地区：[1]武汉市疾病预防控制中心传染病防制所,湖北武汉430015

出　　处：《中华疾病控制杂志》2011年第8期701-704,共4页Chinese Journal of Disease Control & Prevention

摘　　要：目的分析2004-2009年武汉市甲、戊型病毒性肝炎的发病情况和变化趋势。方法采用描述性流行病学方法对2004-2009年武汉市甲型、戊型病毒性肝炎报告病例的流行病学特征进行分析,统计学方法采用χ2检验、Pearson列联系数、集中度M值。结果 2004-2009年武汉市报告甲肝1 376例、戊肝4 044例,年平均发病率分别为2.81/10万和8.25/10万。甲肝发病率较低,呈逐年下降趋势;戊肝发病率较高,有下降趋势。甲肝和戊肝呈常年散发,无明显季节性分布。年平均发病率方面,甲肝中心城区低于远城区,戊肝中心城区高于远城区（均有P〈0.001）;甲肝、戊肝发病率均随年龄增加而上升（甲肝：χ2=282.85,P〈0.001,r=0.28,P〈0.001;戊肝：χ2=320.37,P〈0.001,r=0.30,P〈0.001）,50~79岁较高,男性高于女性（P〈0.001）。职业分布上,甲肝以农民为主,占31.32%;戊肝以离退休人员为主,占29.35%。结论武汉市近年来甲肝发病率较低,且呈逐年下降趋势,远城区是高发区;戊肝发病率较高,中心城区是高发区。男性、50岁以上老年人是甲、戊肝发病的重点人群。Objective To analyze the incidence and epidemiological trend of hepatitis A and hepatitis E viral in Wuhan City from 2004 to 2009.Methods Descriptive epidemiological study was conducted.Statistical methods including Chi-Square test,Pearson contingency coefficient and concentration ratio were used.Results 1 376 cases of Hepatitis A and 4 044 cases of Hepatitis E were reported in Wuhan City from 2004 to 2009. The average incidences of them were 2.81 per 100 000 and 8.25 per 100 000 respectively.Incidence of Hepatitis A was low,which was high with Hepatitis E,and they both had a downward trend.Annual distribution of cases of Hepatitis A and Hepatitis E had no obvious seasonal fluctuations.The average incidence of Hepatitis A was lower in urban than in rural and of Hepatitis E was higher in urban than in rural（P0.001）,which rose gradually by age（Hepatitis A： χ2=282.85,P0.001,r=0.28,P0.001;Hepatitis E： χ2=320.37,P0.001,r=0.30,P0.001） and were the highest from 50 to 79 year old,and which were higher in male than in female（P0.001）.Among the total cases,farmers accounted for 31.32 percent of Hepatitis A and retirees accounted for 29.35 percent of Hepatitis E.Conclusions In recent years,the incidence of Hepatitis A was low,having a declining trend,which was higher in rural,the incidence of Hepatitis E was high,having a declining trend,which was higher in urban,the key population of Hepatitis A and Hepatitis E were males and the people aged over fifty.

关 键 词：肝炎病毒 甲型 肝炎病毒 戊型 发病率 流行病学研究 

分 类 号：R181.1[医药卫生—流行病学] R512.6[医药卫生—公共卫生与预防医学]