微波辐射催化合成水杨酸异戊酯  

SYNTHESIS OF ISOAMYL SALICYLATE UNDER MICROWAVE IRRADIATION

作　　者：曹汉迪[1] 丁淮军[1] 陈赞安[1] 吴旭辉[1] 张立庆[1] 

机构地区：[1]浙江科技学院生物与化学工程学院,浙江杭州310023

出　　处：《精细石油化工》2011年第4期4-6,共3页Speciality Petrochemicals

基　　金：浙江省自然科学基金项目(Y404082);浙江省教育厅重点科技项目(20030836)

摘　　要：以水杨酸和异戊醇为原料，运用微波辐射催化合成水杨酸异戊酯。通过L16（4^4）正交实验，用Matlab对实验数据进行最优化处理，讨论了各因素对收率的影响。结果表明：在n（水杨酸）：n（异戊醇）=1：5，V（催化剂）=1．5mL，微波输出功率325W，辐射时间40rain条件下，水杨酸异戊酯收率为84．9％。Isoamyl salicyiate was synthesized with salicylic acid and isoamyl alcohol as raw materialsunder microwave irradiation. Using L16 （4^4）orthogonally arranged experiments with the Matlab optimization, the factors influencing the synthesis were discussed. The results by the orthogonally arranged experiments showed that the optimal conditions were. the molar ratio of salicylic acid to Isoamyl alcohol of 1 ： 5, 1.5 mL sulfuric acid as catalyst, microwave power 325 W and microwave irradiation time 40 min. Under these conditions, the esterification yield could reach 84.9%.

关 键 词：水杨酸异戊酯 微波辐射合成 回归正交试验工艺优化 

分 类 号：TQ656.1[化学工程—精细化工]