颈椎郎格罕细胞组织细胞增生症的MR征象分析  

Magnetic resonance imaging findings of cervical Langerhans＇ cell histiocytosis

作　　者：庞超楠[1] 刘晓光[2] 袁慧书[1] 

机构地区：[1]北京大学第三医院放射科,北京100191 [2]北京大学第三医院骨科,北京100191

出　　处：《实用放射学杂志》2011年第8期1142-1144,1149,共4页Journal of Practical Radiology

基　　金：国家自然科学基金（30840081）.

摘　　要：目的探讨颈椎郎格罕细胞组织细胞增生症的MR表现。方法回顾分析25例经病理证实的颈椎郎格罕细胞组织细胞增生症的MR征象。结果25例中有2例为多发病变，4例有邻近椎骨侵犯，7例累及脊椎前部结构，18例同时累及椎骨的前、后部结构，24例椎体有压缩，25例可见软组织肿块。全部病例在T1WI上为等、稍低或低信号，在T2WI上为稍高或高信号，脂肪抑制序列上为高信号，13例行增强扫描病变均明显强化，无坏死囊变。20例在脊柱长轴方向上侵犯的范围超过受累脊椎水平，17例软组织侵犯椎管，呈局限性生长。结论颈椎郎格罕细胞组织细胞增生症的MR征象具有一定特征性，对该病的诊断具有较大的帮助，但确诊仍需依靠病理活检。Objective To study the MR findings of the cervical Langerhans＇ cell histiocytosis（LCH）. Methods MR findings were retrospectively analyzed in 25 cases of Langerhans＇ cell histiocytosis. All cases were confirmed pathologically. Results In all the 25 cases, 2 of 25 cases had multiple lesions, and adjacent vertebrae involved in 4, the anterior structure of vertebral involved in 7, both vertebral body and appendix involved in 18. Different degree of vertebral compression were found in 24 cases, and soft-tissue masses were found in all cases. All lesions were presented as hypo-isointensity on T1WI, hyperintensity on T2WI and STIR. The lesions in 13 cases with significant enhancement after Gd-DTPA injection and without cystic necrosis. The intraspinal canals were involved locally,the ranges of the soft-tissue masses in 20 cases beyond the bone lesions. Conclusion MRI findings of cervical LCH can be regarded as characteristic,which were helpful for diagnOsis,but the definite diagnosis is depending on biopsy.

关 键 词：颈椎 郎格罕细胞组织细胞增生症 磁共振成像 

分 类 号：R681.5[医药卫生—骨科学] R445.2[医药卫生—外科学]