寻常型银屑病诱发因素分析  

Causative Factors of Psoriasis Vulgaris

作　　者：魏瑾[1] 刘梅[1] 肖汀[1] 曲乐[1] 陈洪铎[1] 何春涤[1] 

机构地区：[1]中国医科大学附属第一医院皮肤科,辽宁省沈阳市110001

出　　处：《中国全科医学》2011年第24期2783-2785,共3页Chinese General Practice

基　　金：教育部创新团队基金(IRT0760);辽宁省教育厅创新团队基金(2008T193)

摘　　要：目的探讨寻常型银屑病的诱发因素。方法选取426例寻常型银屑病患者(病例组)和500例健康者(对照组)。应用病例对照研究方法,对两组受检者的10种因素进行单因素和多因素分析。结果单因素分析显示,受潮、感染、外伤、饮酒、食鱼虾、药物、精神紧张及吸烟的患者在病例组、对照组中差异有统计学意义(P<0.05)。多元Logistic回归分析显示,除了药物外,其他因素均是寻常型银屑病的诱发因素(P<0.05)。结论多种环境因素在寻常型银屑病的发生、发展中起重要作用。Objective To investigate the causative factors of psoriasis vulgaris. Methods A total of 426 psoriasis vul- garis patients and 500 healthy subjects were enrolled. Through the method of case control study, single factor analysis and multi - factor analysis on ten factors of the case group and the control group subjects were carried out. Results It was showed by single factor analysis that damp conditions, infection, wound, drinking, fish and shrimp, drugs, mental stress and smoke were all among the risk factors of psoriasis with significant differences between the case and the control group （ P 〈 O. 05 ） . Multi - factor analysis revealed that all the factors mentioned above contributed to the pathogenesis of psoriasis vulgaris except for drugs （ P 〈 0.05 ） . Conclusion A number of environmental factors contribute to the development of psoriasis vulgaris.

关 键 词：银屑病 诱发因素 环境 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]