无溶剂法超声波合成水杨酰肼工艺研究  

Synthesis of 2-Hydroxybenzhydrazide by Non-solvent Ultrasonic Method

作　　者：严回[1] 聂丽[2] 田晓雪[1] 涂东怀[1] 郑长征[1] 

机构地区：[1]西安工程大学环境与化学工程学院,陕西西安710048 [2]皖西学院材料与化工学院,安徽六安237012

出　　处：《化工技术与开发》2011年第8期8-9,21,共3页Technology & Development of Chemical Industry

基　　金：陕西省自然科学基金资助项目(2009JM2012)

摘　　要：在超声波条件下,以水杨酸甲酯与水合肼为原料,采用单因素实验方法,在无溶剂环境下合成了水杨酰肼,通过测定熔点和红外光谱对产物进行了表征,并对合成工艺条件进行了研究。结果表明,反应物体积比为1∶4(无溶剂),水浴温度恒温80℃,超声波变频45～80kHz,反应时间60min时收率最大。该法是绿色化学工艺的一种有效方法。By using a single factor test,2-hydroxybenzhydrazide was synthesized by methyl salicylate and hy-drazine hydrate in solvent-free environment under ultrasonic conditions.Structures of the reaction products were identified by means of micro-melting point determination and IR spectra,and the optimum synthesis reaction conditions were studied.The results showed that the volume ratio of reactant was 1∶4（no solvent）,the temper-ature was 80℃,ultrasonic frequency at 45～80 kHz and the reaction time of 60 min.This method was of a significantly effective method in green chemistry.

关 键 词：水杨酰肼 合成 超声波 

分 类 号：TQ225.266[化学工程—有机化工]