腰痛片的质量标准探讨  

Study on Quality Standards of Yaotong Tablets

作　　者：赵江红[1] 高超旭 郭建功 张东彬 

机构地区：[1]河南省安阳市食品药品检验所,河南安阳455000 [2]郑州福瑞堂制药有限公司,郑州450001 [3]郑州豫密药业股份有限公司,郑州452392

出　　处：《中国实验方剂学杂志》2011年第17期110-112,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨和提高腰痛片的质量标准进行。方法:采用TLC法鉴别方中补骨脂、赤芍;采用HPLC法测定方中绿原酸的含量。结果:定性鉴别中检出补骨脂、赤芍,且分离度好、专属性强,阴性对照无干扰。HPLC测定绿原酸在0.118 4～0.592 0μg有较好的线性关系,平均回收率为99.94%,RSD 1.35%。结论:所建立的质量控制方法准确、可靠、专属性强,可以用于腰痛片的质量控制。Objective：To study and revised the quality standards of yaotong tablets.Method： Psoralea Fructus and Paeoniae Radix Rubra were identified by thin layer chromatography（TLC）.The content of chlorogenic acid was determined by High performance liquid chromatography（HPLC）.Result： Psoralea Fructus and Paeoniae Radix Rubra were identified by thin layer chromatography（TLC）.The characteristic identification was distinct and highly specific.chlorogenic acid was linear in the range of 0.118 4-0.592 0 μg.Average recovery was 99.94%,RSD was 1.35%.Conclusion： The quality control method is reliable,accurate and specific.It can be used for quality control of yaotong tablets.

关 键 词：腰痛片 质量标准 高效液相色谱法 

分 类 号：R284.1[医药卫生—中药学]