介入靶向性治疗急性肺栓塞的临床应用  

Clinical application of intrapulmonary interventional therapy for acute pulmonary thromboembolism

作　　者：张天华[1] 姜维良[1] 张英男[1] 

机构地区：[1]哈尔滨医科大学附属第二医院血管外科,150086

出　　处：《中国急救医学》2011年第8期746-749,共4页Chinese Journal of Critical Care Medicine

摘　　要：目的 探讨介入靶向性溶栓并下腔静脉滤器植入治疗对急性肺栓塞的近期疗效.方法 对确诊的15例肺栓塞患者的临床情况进行分析,并给予介入靶向性溶栓并下腔静脉滤器植入术,观察临床症状、体征、血气分析及血流动力学改变、肺动脉开通情况及有无并发症,并进行疗效评价.结果 介入治疗24 h后临床症状明显改善,平均肺动脉压明显降低,血氧分压和血氧饱和度显著提高;Miller评分明显降低.治疗前后比较均具有统计学意义.结论 早期采用介入治疗对尽快改善患者的临床表现和维持血流动力学稳定具有积极意义,而且介入治疗愈早,预后愈佳.总之,对于急性肺栓塞患者介入治疗是一种有效、快捷、经济的方法.Objective To evaluate the effect of intrapulmonary interventional thrombolytic therapy with vena cava filters transplanting methods for patients with acute pulmonary thromboembolism. Methods lntrapulmonary interventional thrombolytie therapy with vena eava filters transplanting methods were performed for 15 patients. Clinical manifestations, blood gas analysis, hemodynamic changes, the recanalization of the pulmonary artery as well as the occurrence of complications were observed. The changes of pulmonary circulation as well as clinical manifestations before and after treatment were compared. Results The clinical symptoms were improved significantly 24 h after intrapulmonary interventional therapy. Compared with the parameters before surgery, mean pulmonary arterial pressure and Miller score were decreased, arterial partial pressure of oxygen and arterial oxygen saturation were increased significantly after surgery. Conclusion Early interventional therapy is of positive significance for improving the clinical manifestations and the maintenance of hemodynamic stability, and the sooner the interventional treatment were performed, the better the prognosis may be. In short, for patients with acute pulmonary embolism, interventional therapy is a time - saving, fast and economical method.

关 键 词：肺栓塞 介入治疗 

分 类 号：R563.5[医药卫生—呼吸系统]