细胞永生化技术及其应用研究进展  

Progress in Research and Application of Cell Immortalization Technology

作　　者：庄金秋[1,2] 梅建国[1,2] 王文秀[1] 沈志强[1] 

机构地区：[1]山东省滨州畜牧兽医研究院,中国山东滨州256600 [2]吉林大学畜牧兽医学院,中国吉林长春130062

出　　处：《生命科学研究》2011年第4期363-368,共6页Life Science Research

基　　金：山东省自然科学基金资助项目(Y2006D26)

摘　　要：细胞永生化是目前细胞生物学研究的热点之一.引起细胞永生化的因素很多,其中端粒酶在这一过程中发挥重要作用.细胞永生化技术在未来的成功应用,不仅为生物制品的研究与开发提供了有力工具,而且也为疾病的诊断与治疗提出了新的思路.就细胞永生化技术的原理、方法、途径及其应用等方面研究进展作一综述.The study on cell immortalization becomes one of the hot research areas of cell biology. Many factors can cause cells immortalization, telomerase plays an important role in the process of cells immortalization. The technology of cells immortalization will be successfully applicated in many areas in the future. It will provide a powerful tool for the research and development of the biological products, and also give out a new method for diagnosis and treatment of disease. An overview of the advance in the principles, methods, approaches as well as applications of the cell immortalization technology was given.

关 键 词：细胞永生化 端粒酶 应用 

分 类 号：Q813.5[生物学—生物工程]