四川省松潘县藏族成人脉压异常与心血管病危险因素和心功能的相关性  

Relation among abnormal pulse pressure and cardiovascular risk factors,cardiac function in Tibetan adults from Songpan county of Sichuan province in China

作　　者：李硕 谢朝辉 韩少梅[2] 齐保申[2] 徐成丽[2] 斯琴[2] 朱广瑾[2] 

机构地区：[1]北京市西城区平安医院,北京100035 [2]中国医学科学院基础医学研究所北京协和医学院基础学院

出　　处：《心血管康复医学杂志》2011年第4期293-296,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：国家科学技术部科技基础性工作专项2006年度项目(2006FY110300)

摘　　要：目的:通过调查中国四川省松潘县藏族成人脉压的分布特点,探讨藏族成人脉压异常与心血管病危险因素和心功能的相关性。方法:采用流行病学横断面的研究方法,对中国四川省松潘县18～74岁的1015名藏族成人的身体健康状况进行随机、分层、整群抽样问卷调查和体格检查。结果:四川松潘县藏族成人平均脉压是(45.59±14.22)mmHg,脉压异常的有143例(14.09%)。多因素线性回归和Logistic回归分析结果显示:脉压异常与年龄呈正相关(OR=1.05,P<0.05),与高密度脂蛋白水平呈负相关(OR=-2.69,P<0.05)。与正常脉压组相比,脉压异常组全身血管阻力(SVR)显著增加[(1112.61±346.74)kPa/L比(1308.27±354.87)kPa/L,t=-4.87],每搏量指数(SI)[(45.68±12.76)ml/m2比(39.45±9.52)ml/m2,t=4.37]]、心输出量指数(CI)[(3.55±1.00)L/min.m2比(3.22±0.54)L/min.m2,t=3.08]显著降低(P均<0.05)。结论:中国四川省松潘县18～74岁藏族成人中脉压异常的比例较高。脉压异常与心血管病危险因素和心功能指标有关。对脉压异常藏族成人进行健康管理具有重要的公共卫生意义。Objective：To explore relation among abnormal pulse pressure（PP） and cardiovascular risk factors,cardiac function in Tibetan adults through survey on distributive characteristics of PP in Tibetan adults from Songpan county,Sichuan province in China.Methods：An cross-section study was carried out in Songpan county,Sichuan province of China.Questionnaire investigation and physical examination were performed by multi-phase,stratified,unequal proportional and random cluster sampling to investigate 1015 Tibetan adults aged 18-74 years.Results：In Songpan county the average PP is（45.59±14.22）mmHg;the incidence rate of abnormal PP was 14.09%（143/1015）.Multifactor linear regression and Logistic regression analysis showed that abnormal PP was positively related with age（OR=1.05,P〈0.05） and negatively related with level of high density lipoprotein（OR=-2.69,P〈0.05）.Compare with normal PP group,systemic vascular resistance [SVR,（1112.61±346.74） kPa/L vs.（1308.27±354.87） kPa/L,t=-4.87] significantly increased,levels of cardiac index [CI,（3.55±1.00） L/min m2 vs.（3.22±0.54） L/min m2,t=3.08] and stroke index [SI,（45.68±12.76） ml/m2 vs.（39.45±9.52） ml/m2,t=4.37] significantly decreased in abnormal PP group（P〈0.05 all）.Conclusion：Abnormal PP is common in Chinese Tibetan adults aged 18～74 years,which associated with cardiovascular risk factors and change of cardiac function.Health management for Tibetan adults with abnormal PP is strongly advocated.

关 键 词：藏族 血压 心血管疾病 危险因素 心室功能 

分 类 号：R544.09[医药卫生—心血管疾病]